202338-77-0

Basic information

• Product Name: (6E,10Z,14E)-16-(tert-Butyl-diphenyl-silanyloxy)-10-cyano-2,6,14-trimethyl-3-oxo-hexadeca-6,10,14-trienoic acid ethyl ester
• CAS NO: 202338-77-0
• Molecular Weight: 613.913
• Mol File: 202338-77-0.mol

Chemical Properties

• CAS DataBase Reference: (6E,10Z,14E)-16-(tert-Butyl-diphenyl-silanyloxy)-10-cyano-2,6,14-trimethyl-3-oxo-hexadeca-6,10,14-trienoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (6E,10Z,14E)-16-(tert-Butyl-diphenyl-silanyloxy)-10-cyano-2,6,14-trimethyl-3-oxo-hexadeca-6,10,14-trienoic acid ethyl ester(202338-77-0)
• EPA Substance Registry System: (6E,10Z,14E)-16-(tert-Butyl-diphenyl-silanyloxy)-10-cyano-2,6,14-trimethyl-3-oxo-hexadeca-6,10,14-trienoic acid ethyl ester(202338-77-0)

Safety Data

• Hazardous Substances Data: 202338-77-0(Hazardous Substances Data)

Upstream product

• 202338-97-4 (2Z,6E)-8-(tert-Butyl-diphenyl-silanyloxy)-6-methyl-2-[(E)-4-methyl-5-(tetrahydro-pyran-2-yloxy)-pent-3-enyl]-octa-2,6-dienenitrile 
• 202339-11-5 (E)-tert-butyl{[5-(3,3-dimethyloxiran-2-yl)-3-methylpent-2-en-1-yl]oxy}diphenylsilane 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 40036-54-2 (E)-5-(3,3-dimethyloxiran-2-yl)-3-methylpent-2-en-1-ol 
• 609-14-3 2-acetylpropanoic acid ethyl ester 
• 202339-01-3 (2Z,6E)-8-(tert-Butyl-diphenyl-silanyloxy)-2-((E)-5-hydroxy-4-methyl-pent-3-enyl)-6-methyl-octa-2,6-dienenitrile 
• 139109-02-7 (E)-6-((tert-butyldiphenylsilyl)oxy)-4-methylhex-4-enal 

Relevant articles and documents

Advanced Tetracycles in a Stereoselective Approach to d,l-Spongiatriol and Related Metabolites: The Use of Radicals in the Synthesis of Angular Electrophores

A stereoselective radical cascade cyclization of polyene 6, containing an α,β-unsaturated cyano group, was employed to control six contiguous chiral centers and to introduce a C-8 angular CN group in tricycle 7. The cyano group was ultimately utilized as an entry to a C-8 angular hydroxymethyl group. Compound 7 was converted into two key tetracycles 22 and 25, respectively, each possessing an intact D-furan ring system and containing the necessary functionality for further chemical elaboration to the highly oxygenated spongians 1-5.