202350-80-9

Upstream product

• 108-42-9 3-chloro-aniline 
• 211384-72-4 2-(4-(N-methyl)carbamoyl-1,2,3-thiadiazol-5-yl)acetic acid 
• 202350-76-3 2-(4-Methylcarbamoyl-[1,2,3]thiadiazol-5-yl)-malonamic acid ethyl ester 

Downstream Products

• 202350-83-2 5-(1-(3-chlorophenyl)-5-hydroxy-1,2,3-triazol-4-yl)-1,2,3-thiadiazol-4-(N-methyl)carboxamide 

Relevant academic research and scientific papers

Synthesis and study of the rearrangements of 5-(1,2,3-triazol-4-yl)- 1,2,3-thiadiazoles

A method for the synthesis of heterocyclic ring conjugates containing 1,2,3-thiadiazole and 1,2,3-triazole nuclei was elaborated. The mechanism of rearrangement (effect of substituents and solvents) was investigated by NMR spectroscopy. A novel domino-type rearrangement involving both heterocycles was discovered.

Domino-type rearrangements in conjugated 5-(1,2,3-triazol-4-yl)1,2,3-thiadiazoles

The novel 5-(1-aryl-1,2,3-triazol-4-yl)1,2,3-thiadiazole-4-(N-methyl)carboxamides were prepared and their isomerisation to the N-arylcarboxamides was studied.The new rearrangement is thought to proceed as a three-step process, involving ring opening, isomerization of diazothiadiazole, and ring closure.