20245-85-6Relevant articles and documents
Specific base recognition of oligodeoxynucleotides by capillary affinity gel electrophoresis using polyacrylamide-poly(9-vinyladenine) conjugated gel
Baba,Tsuhako,Sawa,Akashi,Yashima
, p. 1920 - 1925 (1992)
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UNSATURATED HETEROCYCLIC DERIVATIVES
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Page/Page column 39, (2008/06/13)
This invention relates to compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.
Synthesis and study of a new adenine-acridine tandem, inhibitor of exonuclease III
Belmont, Philippe,Demeunynck, Martine,Constant, Jean-Francois,Lhomme, Jean
, p. 293 - 295 (2007/10/03)
A new heterodimer adenine-chain-acridine containing a mixed amido-guanidinium linker chain was synthesized. To achieve the synthesis a new method of introduction of aminoalkyl chain at position 9 of adenine was designed. The heterodimer interacts specifically with the abasic sites in DNA and inhibits the major base excision repair enzyme in Escherichia coli, Exonuclease III. (C) 2000 Elsevier Science Ltd. All rights reserved.