202460-49-9 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule of the compound.
Explanation
This is the IUPAC name of the compound, which describes the structure and functional groups present in the molecule.
Explanation
The CAS (Chemical Abstracts Service) number is a unique identifier assigned to a specific chemical compound, used for easy identification and referencing.
Explanation
The compound is derived from 1,3-Propanediamine, which means it is structurally related and contains similar functional groups.
Explanation
The nitro-2-pyridinyl group is a functional group attached to the 1,3-Propanediamine, which gives the compound its unique properties and reactivity.
Explanation
The compound may be used as a starting material or intermediate in the synthesis of various organic compounds, particularly in the pharmaceutical industry.
Explanation
Due to its chemical properties, the compound can pose health risks if not handled properly. It is essential to follow safety protocols and use appropriate protective measures when working with this compound.
Derivative
1,3-Propanediamine
Functional group
Nitro-2-pyridinyl
Industrial and pharmaceutical applications
Building block in the synthesis of organic compounds
Safety
Toxic and harmful if not used correctly
Check Digit Verification of cas no
The CAS Registry Mumber 202460-49-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,2,4,6 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 202460-49:
(8*2)+(7*0)+(6*2)+(5*4)+(4*6)+(3*0)+(2*4)+(1*9)=89
89 % 10 = 9
So 202460-49-9 is a valid CAS Registry Number.
202460-49-9Relevant articles and documents
Synthesis and Evaluation of Bifunctional Aminothiazoles as Antiretrovirals Targeting the HIV-1 Nucleocapsid Protein
Mori, Mattia,Dasso Lang, Maria Chiara,Saladini, Francesco,Palombi, Nastasja,Kovalenko, Lesia,De Forni, Davide,Poddesu, Barbara,Friggeri, Laura,Giannini, Alessia,Malancona, Savina,Summa, Vincenzo,Zazzi, Maurizio,Mely, Yves,Botta, Maurizio
supporting information, p. 463 - 468 (2019/04/25)
Small molecule inhibitors of the HIV-1 nucleocapsid protein (NC) are considered as promising agents in the treatment of HIV/AIDS. In an effort to exploit the privileged 2-amino-4-phenylthiazole moiety in NC inhibition, here we conceived, synthesized, and tested in vitro 18 NC inhibitors (NCIs) bearing a double functionalization. In these NCIs, one part of the molecule is deputed to interact noncovalently with the NC hydrophobic pocket, while the second portion is designed to interact with the N-terminal domain of NC. This binding hypothesis was verified by molecular dynamics simulations, while the linkage between these two pharmacophores was found to enhance antiretroviral activity both on the wild-type virus and on HIV-1 strains with resistance to currently licensed drugs. The two most interesting compounds 6 and 13 showed no cytotoxicity, thus becoming valuable leads for further investigations.
Inhibitors of glycogen synthase kinase 3
-
, (2008/06/13)
Novel pyridine and pyrimidine derivatives which selectively inhibit glycogen synthase kinase 3 are provided and methods of preparing these compounds are provided. These compounds are useful in treating certain conditions which may be mediated by glycogen synthase kinase 3.
