202476-38-8

Basic information

• Product Name: diethyl 3-(4-methoxybenzoyl)oxy-1(E)-propenylphosphonate
• Synonyms: diethyl 3-(4-methoxybenzoyl)oxy-1(E)-propenylphosphonate
• CAS NO: 202476-38-8
• Molecular Weight: 328.302
• Mol File: 202476-38-8.mol

Chemical Properties

• CAS DataBase Reference: diethyl 3-(4-methoxybenzoyl)oxy-1(E)-propenylphosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 3-(4-methoxybenzoyl)oxy-1(E)-propenylphosphonate(202476-38-8)
• EPA Substance Registry System: diethyl 3-(4-methoxybenzoyl)oxy-1(E)-propenylphosphonate(202476-38-8)

Safety Data

• Hazardous Substances Data: 202476-38-8(Hazardous Substances Data)

Upstream product

• 113201-17-5 (E)-diethyl (3-acetoxy-1-propenyl)phosphonate 
• 66498-59-7 diethyl ((E)-3-bromoprop-1-en-1-yl)phosphonate 
• 18689-32-2 diethyl (E)-1-propenylphosphonate 
• 100-07-2 4-methoxy-benzoyl chloride 
• 76242-00-7 diethyl (1E)-3-hydroxyprop-1-enylphosphonate 

Downstream Products

• 202476-41-3 diethyl (1S,2S)-1,2-dihydroxy-3-(4-methoxybenzoyloxy)propylphosphonate 

Relevant articles and documents

Enantioselective synthesis of threo-α,β-dihydroxyphosphonates by asymmetric dihydroxylation of 1(E)-alkenylphosphonates with AD-mix reagents

Asymmetric dihydroxylation (AD) of 1(E)-alkenylphosphonates with an AD- mix-α or -β reagent was examined to give a series of optically active threo-α,β-dihydroxyphosphonates. Good enantioselectivity (>88% ee) was observed in the AD reaction of 1(E)-alkenylphosphonates with conjugated aromatic substituents. The steric effects of the ester functionality in the course of the dihydroxylation were also evaluated. Enantioselectivity and yield were significantly improved when the AD reaction was carded out with dimethyl phosphonate instead of diethyl phosphonate.