202477-94-9

Basic information

• Product Name: L-Alanine, 3-amino-, 1,1-dimethylethyl ester (9CI)
• Synonyms: L-Alanine, 3-amino-, 1,1-dimethylethyl ester (9CI)
• CAS NO: 202477-94-9
• Molecular Formula: C7H16N2O2
• Molecular Weight: 160.21414
• Product Categories: GLYCINESCAFFOLD
• Mol File: 202477-94-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: L-Alanine, 3-amino-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: L-Alanine, 3-amino-, 1,1-dimethylethyl ester (9CI)(202477-94-9)
• EPA Substance Registry System: L-Alanine, 3-amino-, 1,1-dimethylethyl ester (9CI)(202477-94-9)

Safety Data

• Hazardous Substances Data: 202477-94-9(Hazardous Substances Data)

Upstream product

• 109273-23-6 2,3-di(benzyloxycarbonylamino)propionic acid t-butyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 4013-43-8 ethylene-1,2-diamine 

Downstream Products

• 166410-28-2 N-(tert-butyloxycarbonyl)-N'-(9H-fluoren-9-ylmethoxycarbonyl)-1,2-diaminoethane 

Relevant articles and documents

Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility

A novel class of compounds known as peptide nucleic acids, bind complementary DNA and RNA strands, and generally do so more strongly than the corresponding DNA or RNA strands while exhibiting increased sequence specificity and solubility. The peptide nucleic acids comprise ligands selected from a group consisting of naturally-occurring nucleobases and non-naturally-occurring nucleobases, including 2,6-diaminopurine, attached to a polyamide backbone, and contain alkyl amine side chains.

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Peptide nucleic acids having 2,6-diaminopurine nucleobases

A novel class of compounds, known as peptide nucleic acids, bind complementary DNA and RNA strands more strongly than a corresponding DNA strand, and exhibit increased sequence specificity and binding affinity. The peptide nucleic acids of the invention comprise ligands selected from a group consisting of naturally-occurring nucleobases and non-naturally-occurring nucleobases attached to a polyamide backbone. Some PNAs of the invention also contain C1-C8alkylamine side chains.

Double-stranded peptide nucleic acids

A novel class of compounds, known as peptide nucleic acids, form double-stranded structures with one another and with ssDNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide backbone through a suitable linker.

Vitronectin receptor antagonists

PCT No. PCT/US98/00490 Sec. 371 Date Jun. 29, 1999 Sec. 102(e) Date Jun. 29, 1999 PCT Filed Jan. 8, 1998 PCT Pub. No. WO98/30542 PCT Pub. Date Jul. 16, 1998This invention relates to certain tricyclic compounds that are integrin receptor antagonists.

Integrin receptor antagonists

Compounds of formula (I) STR1 wherein A1 is C or N; E is a five- or six-membered heteroaromatic or six-membered aromatic ring optionally substituted by R3 or R4 ; X1 --X2 is CHR1 --CH, CR1 =CH, NR1 --CH, S(O)u --CH or O--CH; X3 is CR5 R5 ', NR5, S(O)u or O; R2 is --OR', --NR'R", --NR'SO2 R'", --NR'OR', --OCR'2 C(O)OR', --OCR'2 OC(O)--R', --OCR'2 C(O)NR'2, CF3 or --COCR'2 R2 '; R3, R4 and R7 are independently H, halo, --OR12, --SR12, --CN, --NR'R12, --NO2, --CF3, CF3 S(O)r --, --CO2 R', --CONR'2, R14 --C0-6 alky-, R14 --C1-6 oxoalkyl-, R14 --C2-6 alkenyl-, R14 --C2-6 alkynyl-, R14 --C0-6 alkyloxy-, R14 --C0-6 alkylamino- or R14 --C0-6 alkyl--S(O)r --; R6 is W--(CR'2)q --Z--(CR'R10)--U--(CR'2)s --V-- or W'--(CR'2)q --U--(CR'2)s -- U and V are absent or CO, CR'2, C(=CR152), S(O)n, O, NR15, CR15 'OR15, CR'(OR")CR'2, CR'2 CR'(OR") C(O)CR'2, CR152 C(O), CONR15, NR15 CO, OC(O), C(O)O, C(S)O, OC(S), C(S)NR15, NR15 C(S), SO2 NR15, NR15 SO2, N=N, NR15 NR15, NR15 CR152, NR15 CR152, CR152 O, OCR152, C$(m)ZC, CR15 =CR15, Het, or Ar, provided that U and V are not simultaneously absent, and W and W' are a nitrogen-containing substituent, and integrin receptor antagonists.

Peptide nucleic acids having amino acid side chains

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Topologically segregated, encoded solid phase libraries

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