202533-73-1

Basic information

• Product Name: 3',5'-O-[1,1,3,3-Tetrakis(1-methylethyl)-1,3-disiloxanediyl]uridine 2'-(4-nitrophenyl carbonate)
• Synonyms: 3',5'-O-[1,1,3,3-Tetrakis(1-methylethyl)-1,3-disiloxanediyl]uridine 2'-(4-nitrophenyl carbonate)
• CAS NO: 202533-73-1
• Molecular Weight: 651.818
• Mol File: 202533-73-1.mol

Chemical Properties

• CAS DataBase Reference: 3',5'-O-[1,1,3,3-Tetrakis(1-methylethyl)-1,3-disiloxanediyl]uridine 2'-(4-nitrophenyl carbonate)(CAS DataBase Reference)
• NIST Chemistry Reference: 3',5'-O-[1,1,3,3-Tetrakis(1-methylethyl)-1,3-disiloxanediyl]uridine 2'-(4-nitrophenyl carbonate)(202533-73-1)
• EPA Substance Registry System: 3',5'-O-[1,1,3,3-Tetrakis(1-methylethyl)-1,3-disiloxanediyl]uridine 2'-(4-nitrophenyl carbonate)(202533-73-1)

Safety Data

• Hazardous Substances Data: 202533-73-1(Hazardous Substances Data)

Upstream product

• 7693-46-1 4-Nitrophenyl chloroformate 
• 69304-38-7 3',5'-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)uridine 

Relevant articles and documents

Conjugation of Small Molecules to RNA Using a Reducible Disulfide Linker Attached at the 2′-OH Position through a Carbamate Function

A post-synthesis conjugation method was developed to functionalize oligoribonucleotides with various small molecules of biological interest using a reduction-sensitive disulfide linker connected to 2′OH via a carbamate function. For this, first we prepare

2'-silyl containing thiocarbonate protecting groups for RNA synthesis

Nucleoside monomers, nucleic acids, e.g., oligonucleotides and polynucleotides, methods of making each, methods of deprotecting each, and the like are disclosed herein. Aspects of the invention include 2′ silyl containing thiocarbonate protecting groups.

Chemical Synthesis and Properties of Conformationally Fixed Diuridine Monophosphates as Building Blocks of the RNA Turn Motif

Two intramolecularly cyclized diuridine monophosphates having an amide and a carbamate linker have been synthesized for fixation of the U-turn structure found in various tRNAs and hammerhead ribozymes. The structural analysis of these cyclic dimers using