202590-69-0

Basic information

• Product Name: CIS-4-AMINO-5-CHLORO-2-METHOXY-N-(3-METHOXY-PIPERIDIN-4-YL)-BENZAMIDE
• Synonyms: NORCISAPRIDE;CIS-4-AMINO-5-CHLORO-2-METHOXY-N-(3-METHOXY-PIPERIDIN-4-YL)-BENZAMIDE;Ticalopride;Ticalopride [inn];Unii-qng273A81o;4-amino-5-chloro-2-methoxy-N-((3S,4R)-3-methoxypiperidin-4-yl)benzamide
• CAS NO: 202590-69-0
• Molecular Formula: C₁₄H₂₀ClN₃O₃
• Molecular Weight: 313.78
• Mol File: 202590-69-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 461°Cat760mmHg
• Flash Point: 232.6°C
• Appearance: /
• Density: 1.29g/cm³
• CAS DataBase Reference: CIS-4-AMINO-5-CHLORO-2-METHOXY-N-(3-METHOXY-PIPERIDIN-4-YL)-BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: CIS-4-AMINO-5-CHLORO-2-METHOXY-N-(3-METHOXY-PIPERIDIN-4-YL)-BENZAMIDE(202590-69-0)
• EPA Substance Registry System: CIS-4-AMINO-5-CHLORO-2-METHOXY-N-(3-METHOXY-PIPERIDIN-4-YL)-BENZAMIDE(202590-69-0)

Safety Data

• Hazardous Substances Data: 202590-69-0(Hazardous Substances Data)

Upstream product

• 1171125-92-0 tert-butyl (3S,4R)-4-amino-3-methoxypiperidine-1-carboxylate 
• 7206-70-4 4-amino-5-chloro-2-methoxybenzoic acid 

Downstream Products

• 860174-12-5 Naronapride 

Relevant articles and documents

LUMINALLY-ACTING N-(PIPERIDIN-4-YL)BENZAMIDE DERIVATIVES

Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein m, R1, R2, R3, R4, R5, R6, X1, X2, X3 and X4 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating diseases, disorders, and conditions associated with the 5-HT4 receptor.

PIPERIDINE DERIVATIVES FOR THE TREATMENT OF GASTROINTESTINAL AND CNS DISORDERS

The subject invention provides stereoisomeric compounds of formula (X): wherein the variables are as defined herein, and compositions for the safe and effective treatment of various gastrointestinal disorders including, but not limited to, gastroparesis,