202648-86-0

Basic information

• Product Name: (2R,3S,4S,5R,6R)-6-((2R,3R,4S,5R,6S)-4,5-Bis-benzyloxy-2-benzyloxymethyl-6-methoxy-tetrahydro-pyran-3-yloxy)-2-hydroxymethyl-4-methoxy-2-vinyl-tetrahydro-pyran-3,5-diol
• Synonyms: (2R,3S,4S,5R,6R)-6-((2R,3R,4S,5R,6S)-4,5-Bis-benzyloxy-2-benzyloxymethyl-6-methoxy-tetrahydro-pyran-3-yloxy)-2-hydroxymethyl-4-methoxy-2-vinyl-tetrahydro-pyran-3,5-diol
• CAS NO: 202648-86-0
• Molecular Weight: 666.766
• Mol File: 202648-86-0.mol

Chemical Properties

• CAS DataBase Reference: (2R,3S,4S,5R,6R)-6-((2R,3R,4S,5R,6S)-4,5-Bis-benzyloxy-2-benzyloxymethyl-6-methoxy-tetrahydro-pyran-3-yloxy)-2-hydroxymethyl-4-methoxy-2-vinyl-tetrahydro-pyran-3,5-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S,4S,5R,6R)-6-((2R,3R,4S,5R,6S)-4,5-Bis-benzyloxy-2-benzyloxymethyl-6-methoxy-tetrahydro-pyran-3-yloxy)-2-hydroxymethyl-4-methoxy-2-vinyl-tetrahydro-pyran-3,5-diol(202648-86-0)
• EPA Substance Registry System: (2R,3S,4S,5R,6R)-6-((2R,3R,4S,5R,6S)-4,5-Bis-benzyloxy-2-benzyloxymethyl-6-methoxy-tetrahydro-pyran-3-yloxy)-2-hydroxymethyl-4-methoxy-2-vinyl-tetrahydro-pyran-3,5-diol(202648-86-0)

Safety Data

• Hazardous Substances Data: 202648-86-0(Hazardous Substances Data)

Upstream product

• 202648-84-8 1,2,4,6-tetra-O-acetyl-3-O-methyl-5-C-vinyl-β-D-gluco-pyranose 
• 202648-85-9 methyl 2,3,6-tri-O-benzyl-4-O-(2,4,6-tri-O-acetyl-3-O-methyl-5-C-vinyl-β-D-glucopyranosyl)-α-D-glucano-side 

Downstream Products

• 403725-14-4 methyl (6-O-benzyl-2,3,4-tri-O-methyl-α-D-glucopyranosyl)-(1->4)-(benzyl 5-C-ethyl-2,3-di-O-methyl-β-D-glucopyranosyluronate)-(1->4)-2,3,6-tri-O-benzyl-α-D-glucopyranoside 
• 403725-22-4 methyl 2,3,6-tri-O-benzyl-4-O-(benzyl 2,3-di-O-methyl-5-C-methoxymethyl-α-L-idopyranosyluronate)-α-D-glucopyranoside 
• 229956-33-6 methyl 2,3,6-tri-O-benzyl-4-O-(benzyl 2,3-di-O-methyl-5-C-ethyl-β-D-glucopyranosyluronate)-α-D-glucopyranoside 
• 202648-88-2 Acetic acid (4aR,6R,7S,8S,8aS)-6-((2R,3R,4S,5R,6S)-4,5-bis-benzyloxy-2-benzyloxymethyl-6-methoxy-tetrahydro-pyran-3-yloxy)-8-methoxy-2,2-dimethyl-4a-vinyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl ester 
• 403725-12-2 methyl 2,3,6-tri-O-benzyl-4-O-(2,3-di-O-methyl-5-C-vinyl-β-D-glucopyranosyl)-α-D-glucopyranoside 
• 229956-32-5 methyl 2,3,6-tri-O-benzyl-4-O-(2,3-di-O-methyl-5-C-ethyl-β-D-glucopyranosyl)-α-D-glucopyranoside 
• 229956-30-3 methyl O-(4,6-O-isopropylidene-2,3-di-O-methyl-5-C-vinyl-β-D-glucopyranosyl)-(1→4)-2,3,6-tri-O-benzyl-α-D-glucopyranoside 
• 403725-21-3 methyl 2,3,6-tri-O-benzyl-4-O-(2,3,6-tri-O-methyl-5-C-vinyl-β-D-glucopyranosyl)-α-D-glucopyranoside 
• 202648-90-6 methyl 2,3,6-tri-O-benzyl-4-O-(2-O-acetyl-3-O-methyl-6-O-tosyl-5-C-vinyl-β-D-mannopyranosyl)-α-D-glucopyranoside 
• 202648-92-8 methyl 2,3,6-tri-O-benzyl-4-O-(2,6-anhydro-5-C-benzyloxycarbonyl-3-O-methyl-β-D-mannopyranosyl)-α-D-glucopyranoside 
• 202648-89-3 methyl 2,3,6-tri-O-Benzyl-4-O-(2-O-acetyl-3-O-methyl-5-C-vinyl-β-D-mannopyranosyl)-α-D-glucopyranoside 
• 202648-87-1 methyl 2,3,6-tri-O-Benzyl-4-O-(4,6-O-isopropylidene-3-O-methyl-5-C-vinyl-β-D-mannopyranosyl)-α-D-gluco-pyranoside 
• 202648-91-7 methyl 2,3,6-tri-O-Benzyl-4-O-(2,6-anhydro-3-O-methyl-5-C-vinyl-β-D-mannopyranosyl)-α-D-glucopyranoside 
• 202649-52-3 methyl 2,3,6-tri-O-benzyl-4-O-(4,6-O-isopropylidene-3-O-methyl-5-C-vinyl-β-D-glucopyranosyl)-α-D-glucopyranoside 

Relevant articles and documents

Pentasaccharides processes for their preparation and pharmaceutical compositions containing them

Pentasaccharides in acidic form and their pharmaceutically acceptable salts, the anionic form thereof having the formula: wherein: R represents hydrogen or an —SO3?, (C1-C3)alkyl or (C2-C3)

Synthesis of conformationally locked L-iduronic acid derivatives: Direct evidence for a critical role of the skew-boat 2S0 conformer in the activation of antithrombin by heparin

We have used organic synthesis to understand the role of L-iduronic acid conformational flexibility in the activation of antithrombin by heparin. Among known synthetic analogues of the genuine pentasaccharidic sequence representing the antithrombin bindin