403725-12-2

Upstream product

• 202648-86-0 (2R,3S,4S,5R,6R)-6-((2R,3R,4S,5R,6S)-4,5-Bis-benzyloxy-2-benzyloxymethyl-6-methoxy-tetrahydro-pyran-3-yloxy)-2-hydroxymethyl-4-methoxy-2-vinyl-tetrahydro-pyran-3,5-diol 
• 202648-85-9 methyl 2,3,6-tri-O-benzyl-4-O-(2,4,6-tri-O-acetyl-3-O-methyl-5-C-vinyl-β-D-glucopyranosyl)-α-D-glucano-side 
• 202649-52-3 methyl 2,3,6-tri-O-benzyl-4-O-(4,6-O-isopropylidene-3-O-methyl-5-C-vinyl-β-D-glucopyranosyl)-α-D-glucopyranoside 
• 202648-84-8 1,2,4,6-tetra-O-acetyl-3-O-methyl-5-C-vinyl-β-D-gluco-pyranose 
• 229956-30-3 methyl O-(4,6-O-isopropylidene-2,3-di-O-methyl-5-C-vinyl-β-D-glucopyranosyl)-(1→4)-2,3,6-tri-O-benzyl-α-D-glucopyranoside 

Downstream Products

• 229956-32-5 methyl 2,3,6-tri-O-benzyl-4-O-(2,3-di-O-methyl-5-C-ethyl-β-D-glucopyranosyl)-α-D-glucopyranoside 
• 403725-21-3 methyl 2,3,6-tri-O-benzyl-4-O-(2,3,6-tri-O-methyl-5-C-vinyl-β-D-glucopyranosyl)-α-D-glucopyranoside 
• 229956-33-6 methyl 2,3,6-tri-O-benzyl-4-O-(benzyl 2,3-di-O-methyl-5-C-ethyl-β-D-glucopyranosyluronate)-α-D-glucopyranoside 
• 403725-22-4 methyl 2,3,6-tri-O-benzyl-4-O-(benzyl 2,3-di-O-methyl-5-C-methoxymethyl-α-L-idopyranosyluronate)-α-D-glucopyranoside 
• 403725-14-4 methyl (6-O-benzyl-2,3,4-tri-O-methyl-α-D-glucopyranosyl)-(1->4)-(benzyl 5-C-ethyl-2,3-di-O-methyl-β-D-glucopyranosyluronate)-(1->4)-2,3,6-tri-O-benzyl-α-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis of conformationally locked L-iduronic acid derivatives: Direct evidence for a critical role of the skew-boat 2S0 conformer in the activation of antithrombin by heparin

We have used organic synthesis to understand the role of L-iduronic acid conformational flexibility in the activation of antithrombin by heparin. Among known synthetic analogues of the genuine pentasaccharidic sequence representing the antithrombin bindin