20275-00-7

Basic information

• Product Name: D-Galactose oxime
• Synonyms: D-Galactose oxime;Nsc21564
• CAS NO: 20275-00-7
• Molecular Formula: C₆H₁₃NO₆
• Molecular Weight: 195.17052
• Mol File: 20275-00-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 633.525°C at 760 mmHg
• Flash Point: 435.608°C
• Appearance: /
• Density: 1.66g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.566
• CAS DataBase Reference: D-Galactose oxime(CAS DataBase Reference)
• NIST Chemistry Reference: D-Galactose oxime(20275-00-7)
• EPA Substance Registry System: D-Galactose oxime(20275-00-7)

Safety Data

• Hazardous Substances Data: 20275-00-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H13NO6/c8-2-4(10)6(12)5(11)3(9)1-7-13/h1,3-6,8-13H,2H2/b7-1+/t3-,4+,5+,6-/m0/s1

Upstream product

• 59-23-4 D-Galactose 
• 1990-29-0 D-altrose 
• 1253285-17-4 26-O-β-D-glucopyranosyl-(25R)-5α-furostan-20(22)-en-3β,26-diol-3-O-β-D-xylopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→3)]-β-D-glucopyranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→2)]-β-D-galactopyranoside 
• 3646-73-9 α-D-galactopyranose 

Downstream Products

• 1114-34-7 D-lyxose 
• 35439-42-0 penta-O-acetyl-D-galactonic acid nitrile 
• 86779-05-7 2,3,4,5,6-penta-O-benzoyl-D-galactononitrile 
• 85339-15-7 N-hydroxy-β-D-galactopyranosylamine hexaacetate 
• 56224-19-2 1-(5-chloro-2.4-dinitro-anilino)-D-1-deoxy-galactitol 
• 887905-93-3 1-(2,4-dinitro-anilino)-D-1-deoxy-galactitol 
• 70878-08-9 N-(4-nitro-phenyl)-β-D-lyxopyranosylamine 
• 108873-22-9 1-salicylidenamino-D-1-deoxy-galactitol 

Relevant articles and documents

Determination of [(13)C]galactose enrichment in human plasma by gas chromatography/positive chemical ionization tandem mass spectrometry.

Galactosemia is a potentially fatal disease resulting from a deficiency of galactose-1-phosphate uridyl transferase. In order to perform mechanistic studies designed to elucidate further the etiology of the disease, we required a method to monitor (13)C enrichment in plasma galactose following a single oral dose or intravenous infusion of [1-(13)C]galactose. Determinations of plasma [(13)C]galactose enrichment requires methodology with extremely high specificity because of potential interference from other low molecular mass plasma constituents and from glucose, an isomer which is present in much higher concentrations. We have developed a method based on gas chromatography/positive chemical ionization tandem mass spectrometry (GC/PCI-MS/MS) for the precise and accurate determination of plasma [(13)C]galactose enrichment. The method employed a pentaacetylaldononitrile derivative of galactose in order to improve its GC and MS characteristics. Peak areas resulting from the transitions m/z 328 --> 106 and m/z 329 --> 107 were used to quantify the relative abundance of labeled and unlabeled galactose. Validation of the method was performed by determination of the precision and accuracy over a wide range of galactose concentrations and (13)C enrichments. The GC/PCI-MS/MS method was able to determine accurately enrichments at galactose concentrations down to 0.8 microM in the presence of 4 mM glucose, making it both highly selective and the most sensitive method currently available. Copyright 2000 John Wiley & Sons, Ltd.

Antioxidant activity of a water-soluble polysaccharide purified from Pteridium aquilinum

A water-soluble crude polysaccharide, obtained from fern Pteridium aquilinum, was fractionated by DEAE-Sepharose Fast-Flow column chromatography, and purified by Sephacryl S-400 HR column chromatography. The average molecular weight (Mw) of the purified polysaccharide (PLP) is 458,000 Da. The monosaccharide components of PLP were characterized by gas chromatography (GC), and the majority of the monosaccharide components was glucose (relative mass 58.1%) with low levels of galactose, mannose, rhamnose, and arabinose (relative mass 18.7%, 6.8%, 10.2%, and 6.1%, respectively). The Fourier-transform infrared spectra (FTIR) of PLP revealed typical characteristics of polysaccharides. On the basis of the ferric-reducing antioxidant power assay (FRAP), DPPH radical-scavenging, the superoxide radical assay, and self-oxidation of 1,2,3-phentriol assay, the antioxidant activities of PLP were investigated. The purified polysaccharide was demonstrated to have strong reductive power (FRAP value: 827.6 μmol/L), moderate scavenging activities against DPPH radicals (83.1%) and superoxide radicals (60.5%), and moderate inhibiting power for self-oxidation of 1,2,3-phentriol (52.4%).

Preparation of aldononitrile acetates using N-methylimidazole as catalyst and solvent

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