3646-73-9Relevant articles and documents
Structural determination of a neutral exopolysaccharide produced by Lactobacillus delbrueckii ssp. bulgaricus LBB.B332
Sanchez-Medina, Inmaculada,Gerwig, Gerrit J.,Urshev, Zoltan L.,Kamerling, Johannis P.
, p. 2735 - 2744 (2007)
The neutral exopolysaccharide produced by Lactobacillus delbrueckii ssp. bulgaricus LBB.B332 in skimmed milk was found to be composed of d-glucose, d-galactose, and l-rhamnose in a molar ratio of 1:2:2. Linkage analysis and 1D/2D NMR (1H and 13C) studies carried out on the native polysaccharide as well as on an oligosaccharide generated by a periodate oxidation protocol, showed the polysaccharide to consist of linear pentasaccharide repeating units with the following structure:{A figure is presented}.
Acylated iridoid glycosides with hyaluronidase inhibitory activity from the rhizomes of Picrorhiza kurroa Royle ex Benth
Morikawa, Toshio,Nakanishi, Yusuke,Inoue, Naoki,Manse, Yoshiaki,Matsuura, Hideyuki,Hamasaki, Shinya,Yoshikawa, Masayuki,Muraoka, Osamu,Ninomiya, Kiyofumi
, (2019/11/03)
Seven new acylated iridoid glycosides, picrorhizaosides A–G (1–7), were isolated from the methanol extract of the rhizomes of Picrorhiza kurroa Royle ex Benth. (Plantaginaceae), in addition to six known iridoid glycosides (8–13). The structures of these new iridoids, including their stereochemistry, were determined based on chemical and physicochemical evidence derived from NMR and MS analysis. Of the isolates, picrorhizaosides D (4, IC50 = 43.4 μM) and E (5, 35.8 μM); picrosides I (8, 60.7 μM), II (9, 22.3 μM), and IV (11, 59.2 μM); and minecoside (13, 57.2 μM), exhibited a similar or stronger hyaluronidase inhibitory activity than those of the antiallergic medicines disodium cromoglycate (64.8 μM), ketotifen fumarate (76.5 μM), and tranilast (227 μM).
The method of integrated kinetics and its applicability to the exo-glycosidase-catalyzed hydrolyses of p-nitrophenyl glycosides
Borisova, Anna S.,Reddy, Sumitha K.,Ivanen, Dina R.,Bobrov, Kirill S.,Eneyskaya, Elena V.,Rychkov, Georgy N.,Sandgren, Mats,St?lbrand, Henrik,Sinnott, Michael L.,Kulminskaya, Anna A.,Shabalin, Konstantin A.
, p. 43 - 49 (2015/06/02)
In the present work we suggest an efficient method, using the whole time course of the reaction, whereby parameters kcat, Km and product KI for the hydrolysis of a p-nitrophenyl glycoside by an exo-acting glycoside hydrola