20277-40-1

Basic information

• Product Name: 1,4-difluorobicyclo[2.2.2]octane
• Synonyms: 1,4-Difluorobicyclo[2.2.2]octane; Bicyclo[2.2.2]octane, 1,4-difluoro-
• CAS NO: 20277-40-1
• Molecular Formula: C₈H₁₂F₂
• Molecular Weight: 146.1777
• Mol File: 20277-40-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 144.5°C at 760 mmHg
• Flash Point: 30.6°C
• Density: 1.08g/cm³
• Vapor Pressure: 6.4mmHg at 25°C
• Refractive Index: 1.436
• CAS DataBase Reference: 1,4-difluorobicyclo[2.2.2]octane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-difluorobicyclo[2.2.2]octane(20277-40-1)
• EPA Substance Registry System: 1,4-difluorobicyclo[2.2.2]octane(20277-40-1)

Safety Data

• Hazardous Substances Data: 20277-40-1(Hazardous Substances Data)

Usage

Type of compound

Bicyclic organic compound

Fluorine atoms

Two fluorine atoms attached to carbon atoms at positions 1 and 4

Structure

Unique and stable

Applications

Useful building block for organic synthesis

Field of study

Medicinal chemistry and drug discovery

Structural properties

Valuable tool in the development of advanced materials and functional molecules

Versatility

Important chemical compound with potential applications in various fields of science and industry

Upstream product

• 1194-44-1 1,4-dihydroxybicyclo[2.2.2]octane 
• 81687-89-0 4-methoxy-2-oxobicyclo<2.2.2>octane-1-carboxylic acid 
• 81687-92-5 7-Methoxy-3,4-diaza-tricyclo[5.2.2.0^1,5]undec-4-en-2-one 
• 81687-87-8 methyl 4-methoxy-2-oxobicyclo<2.2.2>octane-1-carboxylate 
• 23062-53-5 methyl 4-hydroxybicyclo<2.2.2>octane-1-carboxylate 
• 773-34-2 4-methoxybicyclo<2.2.2>octane-1-carboxylic acid 
• 72653-14-6 1,5-di-tert-butyl 3-ethyl 3-acetylpentane-1,3,5-tricarboxylate 
• 22947-61-1 1-fluoro-4-hydroxybicyclo<2.2.2>octane 
• 81687-90-3 methyl 4-methoxybicyclo<2.2.2>octane-1-carboxylate 
• 78385-85-0 methyl 4-fluorobicyclo<2.2.2>octane-1-carboxylate 
• 78385-84-9 4-fluorobicyclo<2.2.2>octane-1-carboxylic acid 
• 78385-83-8 1-acetyl-4-fluorobicyclo<2.2.2>octane 
• 81687-88-9 ethyl 4-methoxy-2-oxobicyclo<2.2.2>octane-1-carboxylate 
• 81687-91-4 methyl 4-acetoxybicyclo<2.2.2>octane-1-carboxylate 

Relevant articles and documents

Synthesis of 4-Substituted Bicyclooct-1-yl Fluorides

The main details of the synthesis of a series of 4-substituted (X) bicyclooct-1-yl fluorides (1), which were required for substituent effect studies, are presented.The synthesis of most of these compounds 1, X = NO2, CN, CONH2, COCH3, CHO, OCH3, O