1194-44-1

Usage

Uses

Used in Organic Synthesis:
Bicyclo[2.2.2]octane-1,4-diol is used as a building block in organic synthesis for the creation of more complex organic compounds. Its unique bicyclic structure and hydroxyl groups make it a valuable intermediate in the synthesis of various organic molecules.
Used in Chemical Research:
Bicyclo[2.2.2]octane-1,4-diol is utilized in chemical research to study the properties and reactions of bicyclic compounds. Its reactivity and structural features provide insights into the behavior of similar compounds and contribute to the advancement of organic chemistry.
Used in Pharmaceutical Industry:
Bicyclo[2.2.2]octane-1,4-diol has potential applications in the pharmaceutical industry as a starting material for the development of new drugs. Its chemical properties and structural characteristics can be exploited to design and synthesize bioactive molecules with therapeutic potential.
Used in Specialty Chemicals Production:
Bicyclo[2.2.2]octane-1,4-diol serves as a starting material for the production of specialty chemicals. Its unique structure and functional groups can be used to create high-value chemicals for various applications, such as coatings, adhesives, and polymers.

Upstream product

• 4982-20-1 1,4-dimethylidenecyclohexane 
• 67-64-1 acetone 
• 79-21-0 peracetic acid 
• 141-78-6 ethyl acetate 
• 64-19-7 acetic acid 
• 1659-75-2 Bicyclo<2.2.2.>octan-1,4-dicarbonsauere-ethylester 
• 711-02-4 1,4-bicyclo[2.2.2]octanedicarboxylic acid 
• 17206-90-5 1,4-Diacetoxybicyclo<2.2.2>octane-2,3-dicarboxylic Acid 
• 17206-91-6 1,4-Diacetoxybicyclo<2.2.2>oct-2-ene 
• 78070-56-1 1,4-diethoxy-2-acetoxymethylenebicyclo<2.2.2>octane 
• 78070-43-6 1,4-Diethoxy-bicyclo[2.2.2]oct-2-ene 
• 78070-46-9 1,4-Diethoxy-bicyclo[2.2.2]octane 
• 10364-35-9 1,4-Diacetoxybicyclo<2.2.2>octane 
• 10364-04-2 bicyclo[2.2.2]octane-1,4-dibromide 

Downstream Products

• 1459-96-7 dimethyl bicyclo[2.2.2]octane-1,4-dicarboxylate 
• 826-45-9 Bicyclo<2.2.2>octane-1,4-dimethanol 
• 94994-15-7 4-hydroxymethyl-bicyclo[2.2.2]octane-1-carboxylic acid methyl ester 
• 711-02-4 1,4-bicyclo[2.2.2]octanedicarboxylic acid 
• 931-98-6 1-Iodobicyclo<2.2.2>octane 
• 280-33-1 bicyclo[2,2,2]octane 
• 54774-94-6 4-acetoxybicyclo<2.2.2>octan-1-ol 
• 10364-05-3 1,4-diiodobicyclo<2.2.2>octane 
• 10364-04-2 bicyclo[2.2.2]octane-1,4-dibromide 
• 1123-39-3 1,4-Dichloro-bicyclo<2.2.2>octane 
• 20277-40-1 1,4-Difluor-bicyclo<2.2.2>octan 
• 28099-22-1 1,4-Bicyclo<2,2,2>oktylen-di-p-butoxybenzoat 
• 28099-24-3 1,4-Bicyclo<2,2,2>oktylen-di-p-heptoxybenzoat 
• 28099-21-0 1,4-Bicyclo<2,2,2>oktylen-di-p-propoxybenzoat 

Relevant academic research and scientific papers

PROCESS FOR PREPARING BICYCLO[2.2.2]OCTANE-1,4-DIOL

Provided is a process for preparing bicyclo[2.2.2]octane-1,4-diol starting from cyclohexane-1,4-dione. The diene is reacted with certain trialkylsilyl halides or trimethylsilyl trifluormethanesulfonate in the presence of a non-nucleophilic base to afford a silyl-substituted diene, which is in turn reacted with ethylene and subsequently reduced to provide the title compound.

SYNTHESIS OF BICYCLO[2.2.2]OCTANE DERIVATIVES

Provided is a process for the preparation of certain 1,4-bicyclo[2.2.2]octane derivatives. The new synthetic procedure involves treating 1,4-dimethylene cyclohexane with an oxidizing agent in the presence of a transition metal catalyst to afford an oxo-substituted bicyclo[2.2.2]octane species. This intermediate structure can then be further derivatized. The processes of this disclosure thus affords a novel and simplified means for the commercial production of a wide variety of bicyclo[2.2.2]octane derivatives.

SYNTHESIS OF BICYCLO(2.2.2)OCTANES

Provided is a process for the preparation of certain 1,4- bicyclo[2.2.2]octane derivatives. The new synthetic procedure involves treating 1,4-dimethylene cyclohexane with an oxidizing agent in the presence of a transition metal catalyst comprising a palla

SYNTHESIS OF 1,4-DISUBSTITUTED BICYCLOOCTANES BY THE DIELS-ALDER REACTION

Methods were developed for the synthesis of 1,4-diethoxy-, 1,4-dicyano-, and 1,4-diphenyl-1,3-cyclohexadienes.Their adducts with maleic anhydride, acrylonitrile, acrolein, nitroethylene, fumaronitrile, and α-acetoacrylonitrile were converted into the corresponding substituted bicyclooctanes.The configuration of the diene synthesis products was studied by IR and PMR spectroscopy.

SYNTHESIS OF BRIDGEHEAD BICYCLOOCTANOLS

The paper describes syntheses of bicyclooctan-1-ol, its 4-methyl and 4-phenyl derivatives, and bicyclooctane-1,4-diol.