2028-10-6

Upstream product

• 201230-82-2 carbon monoxide 
• 3815-23-4 N-methyl-[1,1’-biphenyl]-4-carboxamide 
• 14002-51-8 4-biphenyl-carboxylic acid chloride 
• 92-92-2 biphenyl-4-carboxylic acid 
• 90224-73-0 5-bromo-2-methyl-2,3-dihydro-1H-isoindole-1,3-dione 
• 2938-75-2 diphenyl phenylboronate 

Relevant academic research and scientific papers

Selective Ruthenium-Catalyzed Reductive Alkoxylation and Amination of Cyclic Imides

Reported herein, for the first time, is the selective ruthenium-catalyzed reductive alkoxylation and amination of phthalimides/succinimides. Notably, this novel methodology avoids hydrogenation of the aromatic ring and allows methoxylation of substituted imides with good to excellent selectivity for one of the carbonyl groups. The reported method opens the door to the development of new processes for the selective synthesis of various functionalized N-heterocyclic compounds. As an example, intramolecular reductive couplings to afford tricyclic compounds are presented for the first time.

Rhodium(iii)-catalyzed oxidative carbonylation of benzamides with carbon monoxide

An efficient strategy for the oxidative carbonylation of aromatic amides via C-H/N-H activation to form phthalimides using an Rh(iii) catalyst has been developed. The reaction shows a preference for C-H bonds of electron-rich aromatic amides and tolerates a variety of functional groups. The Royal Society of Chemistry 2011.