90224-73-0

Basic information

• Product Name: 4-Bromo-N-methylphthalimide
• Synonyms: 4-Bromo-N-methylphthalimide;5-BroMo-2-Methylisoindoline-1,3-dione;5-bromo-2-methyl-1H-Isoindole-1,3(2H)-dione;4-Bromo-N-methylphthalimide
• CAS NO: 90224-73-0
• Molecular Formula: C₉H₆BrNO₂
• Molecular Weight: 240.05
• Mol File: 90224-73-0.mol
• Article Data: 10

Chemical Properties

• Melting Point: 147.0 to 151.0 °C
• Boiling Point: 333.5 °C at 760 mmHg
• Flash Point: 155.5 °C
• Appearance: /
• Density: 1.729 g/cm³
• Vapor Pressure: 0.000136mmHg at 25°C
• Refractive Index: 1.64
• Storage Temp.: 2-8°C
• PKA: -3.05±0.20(Predicted)
• CAS DataBase Reference: 4-Bromo-N-methylphthalimide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-N-methylphthalimide(90224-73-0)
• EPA Substance Registry System: 4-Bromo-N-methylphthalimide(90224-73-0)

Safety Data

• Hazardous Substances Data: 90224-73-0(Hazardous Substances Data)

Usage

General Description

4-Bromo-N-methylphthalimide is a chemical compound with the molecular formula C9H7BrNO2. It is a derivative of the phthalimide family and contains a bromine atom and a methyl group attached to the nitrogen atom. 4-Bromo-N-methylphthalimide is commonly used as a reagent in organic synthesis and as a precursor in the production of various pharmaceuticals and agrochemicals. It is known for its ability to undergo nucleophilic substitution reactions, and its unique combination of functional groups makes it a valuable building block in the synthesis of complex organic molecules. Additionally, 4-Bromo-N-methylphthalimide is also used as a reagent for the selective bromination of aromatic compounds. Overall, this compound has various applications in organic chemistry and plays a crucial role in the development of new drugs and agrochemicals.

InChI:InChI=1/C9H6BrNO2/c1-11-8(12)6-3-2-5(10)4-7(6)9(11)13/h2-4H,1H3

Upstream product

• 550-44-7 N-methylphthalimide 
• 586-75-4 4-chlorobenzoyl chloride 
• 586-76-5 4-Bromobenzoic acid 
• 201230-82-2 carbon monoxide 
• 27466-83-7 4-bromo-N-methylbenzamide 
• 6941-75-9 5-Bromoisoindoline-1,3-dione 
• 74-88-4 methyl iodide 
• 70478-63-6 6-bromophthalimide 
• 86-90-8 4-bromophthalic anhydride 
• 74-89-5 methylamine 
• 2307-00-8 4-amino-N-methylphthalimide 

Downstream Products

• 54395-52-7 4,4’-bisphenol A-bis-N-methylphthalimide 
• 57830-14-5 5-phenoxy-3H-isobenzofuran-1-one 
• 63197-24-0 4-phenoxy-N-methyl phthalimide 
• 550-44-7 N-methylphthalimide 

Relevant articles and documents

Bright near-infrared chemiluminescent dyes: Phthalhydrazides conjugated with fluorescent BODIPYs

A series of phthalhydrazides conjugated with NIR fluorescent BODIPY dyes were synthesized (three steps, overall yields 68–83%) and found to show strong NIR chemiluminescence (CL) with maxima in the range of 670–736 nm. One of these showed a CL quantum yield reaching 8.4 times higher than that of luminol. Tuning of the fluorescence band of the BODIPY unit directly leads to a red-shifted CL, developing a strategy for designing NIR chemiluminogens.

High-selectivity aggregation induced chemiluminiscence probe for O2 as well as preparation method and application of chemiluminiscence probe

The invention discloses a high-selectivity aggregation induced chemiluminiscence probe for O2 as well as a preparation method and an application of the chemiluminiscence probe. The structural formula of the chemiluminiscence probe is shown in the descr

Synthesis of biologically potent novel 5-(2-bromopyridin-3-yl-amino)-2- alkyl/aryl-isoindoline-1,3-dione analogs via buchwald-hartwig c-n coupling reaction

A novel series of N-alkyl/aryl substituted phthalimide analogs containing 2-bromopyridyl functionality were synthesized applying optimized Buchwald-Hartwig amination conditions using palladium acetate, cesium carbonate, and =BINAP in toluene at 110°C unde