202865-76-7 Usage
Uses
Used in Pharmaceutical Industry:
2'-BROMO-5'-FLUORO-4'-METHYLACETANILIDE is used as a building block for the production of pharmaceuticals due to its analgesic and anti-inflammatory properties. It serves as a valuable intermediate in the development of new drugs that can potentially treat pain and inflammation.
Used in Agrochemical Industry:
2'-BROMO-5'-FLUORO-4'-METHYLACETANILIDE is used as a building block in the production of agrochemicals, contributing to the development of new compounds that can be used in agriculture for pest control and crop protection.
Used as a Reagent in Organic Synthesis:
2'-BROMO-5'-FLUORO-4'-METHYLACETANILIDE is used as a reagent in the synthesis of various organic compounds, facilitating the creation of new chemical entities for research and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 202865-76-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,2,8,6 and 5 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 202865-76:
(8*2)+(7*0)+(6*2)+(5*8)+(4*6)+(3*5)+(2*7)+(1*6)=127
127 % 10 = 7
So 202865-76-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H9BrFNO/c1-5-3-7(10)9(4-8(5)11)12-6(2)13/h3-4H,1-2H3,(H,12,13)
202865-76-7Relevant academic research and scientific papers
Intermediate for synthesizing camptothecin derivative as well as preparation method and application thereof
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Paragraph 0105-0106, (2020/08/09)
The invention relates to the technical field of organic compound synthesis, in particular to an intermediate for synthesizing a camptothecin derivative as well as a preparation method and applicationof the intermediate. An intermediate A can be obtained by acylation, bromination and cross coupling reaction of 3-fluoro-4-methylaniline. The intermediate A can be used for preparing an intermediate Bso as to further prepare Exatecan mesylate. The intermediate compound B can be obtained by rearrangement reaction of the intermediate A; Exatecan mesylate can be obtained by subjecting the intermediate compound B to alpha-site acetamido and amino deprotection, condensation reaction and hydrolysis reaction. The method has the advantages of low price of reaction initiators, mild reaction conditionsof each step, simplicity and convenience in operation, high yield and suitability for industrial production.
