202865-77-8

Usage

Uses

Used in Pharmaceutical Industry:
2-Bromo-4-Fluoro-6-Methyl Aniline is used as an intermediate compound for the synthesis of various pharmaceutical products. Its unique chemical properties allow it to be incorporated into the structure of drugs, potentially enhancing their efficacy and therapeutic applications.
Used in Catalyst Applications:
2-Bromo-4-Fluoro-6-Methyl Aniline is used as a catalyst in various organic reactions. Its ability to bind with different chemical structures facilitates the acceleration of reaction rates, making it a valuable component in the synthesis of complex organic molecules.
Used in Laboratory Research:
2-Bromo-4-Fluoro-6-Methyl Aniline is used as a research compound for studying its chemical reactivity and potential applications in the formation of new compounds. Its unique properties make it an interesting subject for scientific investigation and the development of novel chemical processes.

InChI:InChI=1/C7H7BrFN/c1-4-2-5(9)3-6(8)7(4)10/h2-3H,10H2,1H3

Upstream product

• 452-71-1 4-fluor-2-methylaniline 

Downstream Products

• 916792-09-1 2-bromo-4-fluoro-6-methylbenzonitrile 
• 1262396-02-0 2-bromo-4-fluoro-6-methylbenzamide 
• 1262396-04-2 2-bromo-4-fluoro-6-methylbenzoic acid methyl ester 
• 877151-43-4 2-cyano-4-fluoro-6-methylbenzoic acid methyl ester 
• 1616975-28-0 C₁₂H₁₆FNSi 
• 1616975-26-8 C₉H₈FN 
• 1616975-05-3 N-(2-ethynyl-4-fluoro-6-methylphenyl)-4-methylbenzenesulfonamide 
• 1000576-68-0 1-bromo-2-chloro-5-fluoro-3-methylbenzene 
• 1100214-35-4 7-bromo-5-fluoro-1H-indazole 
• 1054568-26-1 (E)-4-fluoro-2-methyl-6-styrylaniline 

Relevant academic research and scientific papers

QUINOXALINE DERIVATIVES AS MODULATORS OF THE GLUCOCORTICOID RECEPTOR

The present invention relates to compounds according to general formula (I) which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.

Direct Synthesis of Structurally Divergent Indole Alkaloids from Simple Chemicals

A direct and structurally divergent synthesis of indole alkaloids from very simple 2-vinylanilines, alkynes and TBN via a novel substrate fragmentation/cycloaddition strategy has been developed, which provides an efficient noble-metal-free approach to access a library of highly valuable indole derivatives of tryptamines and tryptamine-related oximes, lactams, and lactones, as well as β-carbolines, spiroindolines, and hexa-hydropyrrolo[2,3-b]indoles.

4-CARBOXAMIDO-ISOINDOLINONE DERIVATIVES AS SELECTIVE PARP-1 INHIBITORS

There are provided substituted 4-carboxamido-isoindolinone derivatives which selectively inhibit the activity of poly (ADP-ribose) polymerase PARP-1 with respect to poly (ADP-ribose) polymerase PARP-2. The compounds of this invention are therefore useful in treating diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds

3-0X0-2, 3, -DIHYDRO-LH-ISOINDOLE-4-CARBOXAMIDES WITH SELECTIVE PARP-1 INHIBITION

There are provided substituted 3 -oxo - 2, 3 -dihydro- 1H-isoindole-4-carboxamide derivatives (I) which selectively inhibit the activity of poly (ADP-ribose) polymerase PARP-1 with respect to poly (ADP-ribose) polymerase PARP-2. The compounds of this invention are therefore useful in treating diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds.