202865-77-8

Basic information

• Product Name: 2-BROMO-4-FLUORO-6-METHYLANILINE
• Synonyms: 2-BROMO-4-FLUORO-6-METHYLANILINE;2-Bromo-4-fluoro-6-methylaniline 98%;2-Bromo-4-fluoro-6-methylaniline98%;2-broMo-4-fluoro-6-MethylbenzenaMine;BenzenaMine, 2-broMo-4-fluoro-6-Methyl-;2-BroMo-4-fluoro-6-Methylaniline, 97+%
• CAS NO: 202865-77-8
• Molecular Formula: C₇H₇BrFN
• Molecular Weight: 204.04
• Product Categories: Amines;C7;Nitrogen Compounds;Aryl Fluorinated Building Blocks;Building Blocks;C7-C8;Chemical Synthesis;Fluorinated Building Blocks;Nitrogen Compounds;Organic Building Blocks;Organic Fluorinated Building Blocks;Other Fluorinated Organic Building Blocks
• Mol File: 202865-77-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 32-36°C
• Boiling Point: 248.879 °C at 760 mmHg
• Flash Point: 110 °C
• Appearance: /
• Density: 1.589 g/cm³
• Vapor Pressure: 0.0237mmHg at 25°C
• Refractive Index: 1.584
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 2.45±0.10(Predicted)
• CAS DataBase Reference: 2-BROMO-4-FLUORO-6-METHYLANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-4-FLUORO-6-METHYLANILINE(202865-77-8)
• EPA Substance Registry System: 2-BROMO-4-FLUORO-6-METHYLANILINE(202865-77-8)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 20/21/22-36/37/38-22
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 202865-77-8(Hazardous Substances Data)

Usage

General Description

2-Bromo-4-Fluoro-6-Methyl Aniline is a specialized chemical compound. It has the molecular formula of C7H8BrFN and is commonly used in the pharmaceutical industry and also as a catalyst in various organic reactions. The chemical properties of this compound are largely determined by the presence of Bromo, Fluoro, Aniline groups and a Methyl group. These give the compound its unique chemical reactivity and characteristic properties. It is essential to handle this compound with care due to its reactive nature which can potentially initiate harmful reactions if not properly managed. Its specific binding to different chemical structures can be highly useful in the formation of new compounds in the laboratory setting.

InChI:InChI=1/C7H7BrFN/c1-4-2-5(9)3-6(8)7(4)10/h2-3H,10H2,1H3

Upstream product

• 452-71-1 4-fluor-2-methylaniline 

Downstream Products

• 916792-09-1 2-bromo-4-fluoro-6-methylbenzonitrile 
• 1262396-02-0 2-bromo-4-fluoro-6-methylbenzamide 
• 1262396-04-2 2-bromo-4-fluoro-6-methylbenzoic acid methyl ester 
• 1616975-28-0 C₁₂H₁₆FNSi 
• 1616975-26-8 C₉H₈FN 
• 1616975-05-3 N-(2-ethynyl-4-fluoro-6-methylphenyl)-4-methylbenzenesulfonamide 
• 1000576-68-0 1-bromo-2-chloro-5-fluoro-3-methylbenzene 
• 877151-43-4 2-cyano-4-fluoro-6-methylbenzoic acid methyl ester 
• 1100214-35-4 7-bromo-5-fluoro-1H-indazole 
• 1054568-26-1 (E)-4-fluoro-2-methyl-6-styrylaniline 

Relevant articles and documents

QUINOXALINE DERIVATIVES AS MODULATORS OF THE GLUCOCORTICOID RECEPTOR

The present invention relates to compounds according to general formula (I) which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.

4-CARBOXAMIDO-ISOINDOLINONE DERIVATIVES AS SELECTIVE PARP-1 INHIBITORS

There are provided substituted 4-carboxamido-isoindolinone derivatives which selectively inhibit the activity of poly (ADP-ribose) polymerase PARP-1 with respect to poly (ADP-ribose) polymerase PARP-2. The compounds of this invention are therefore useful in treating diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds