202869-54-3

Upstream product

• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 746641-73-6 (R)-3-Bromo-3,3-difluoro-2-(4-methoxy-phenylamino)-propionic acid ethyl ester 
• 746641-74-7 ethyl (R)-2-[N-(p-methoxyphenyl)amino]-3,3-difluoro-5-hexenoate 
• 746641-75-8 benzyl (R)-2-[N-(p-methoxyphenyl)amino]-3,3-difluoro-5-hexenoate 

Relevant academic research and scientific papers

First synthesis of 3,3-difluoroserine and cysteine derivatives via Mg(0)-promoted selective C-F bond cleavage of trifluoromethylimines

3,3-Difluoroserine and cysteine derivatives were synthesized via Mg(0)-promoted defluorination of trifluoromethylimines as a key step, followed by addition of alcohols and sulfenyl chloride, respectively. (C) 2000 Elsevier Science Ltd.

N-TMS-β,β-difluoroenamines: Electrochemical preparation and its transormation

The first preparation of N-trimethylsilylated β,β-difluoroenamines (2) from the trifluoromethyl imines (1) by electrochemical reduction and a preliminary study on alkylation of 2 for the synthesis of difluoromethylene compounds are described.