20317-25-3

Usage

Structure

Contains a triazole ring with a carboxamide and an amino group, and a phenyl group attached to one of the nitrogen atoms

Type

Triazole derivative

Potential applications

Pharmaceutical and medicinal chemistry, drug development, synthesis of biologically active compounds

Use as building block

Synthesis of various heterocyclic compounds

Potential inhibitor

For various biochemical processes

InChI:InChI=1/C9H9N5O/c10-8-7(9(11)15)12-13-14(8)6-4-2-1-3-5-6/h1-5H,10H2,(H2,11,15)

Upstream product

• 62-53-3 aniline 
• 622-37-7 Phenyl azide 
• 107-91-5 cyanoacetic acid amide 

Downstream Products

• 103754-03-6 5-anilino-1H-[1,2,3]triazole-4-carboxylic acid amide 
• 31703-13-6 5-methyl-3-phenyl-3,6-dihydro-[1,2,3]triazolo[4,5-d]pyrimidin-7-one 
• 103912-78-3 5-azido-4-carbamoyl-1-phenyl-1,2,3-triazole 
• 20271-39-0 5-amino-1-phenyl-1H-1,2,3-triazole-4-carbonitrile 
• 175348-19-3 3,5-Diphenyl-3,6-dihydro-[1,2,3]triazolo[4,5-d]pyrimidin-7-one 
• 31771-61-6 5-ethyl-3-phenyl-3,6-dihydro-[1,2,3]triazolo[4,5-d]pyrimidin-7-one 
• 31703-14-7 5-benzyl-3-phenyl-3H-1,2,3-triazolo<4,5-d>pyrimidin-7(6H)-one 
• 114306-16-0 3,7-dihydro-3-phenyl-6H-1,2,3-triazolo<4,5-d>pyrimidin-7-one 
• 116944-01-5 5-Methyl-3-phenyl-3H-1,2,3-triazolo<4,5-d>pyrimidine 
• 116944-04-8 6-benzoyl-6,7-dihydro-5-methyl-3-phenyl-3H-1,2,3-triazolo<4,5-d>pyrimidine-7-carbonitrile 
• 116944-11-7 5-acetamido-α-benzamido-1-phenyl-1H-1,2,3-triazole-4-acetonitrile 
• 116944-05-9 7-chloro-5-methyl-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidine 
• 103912-98-7 5-chloro-4-cyano-1-phenyl-1,2,3-triazole 
• 103912-80-7 5-azido-4-cyano-1-phenyl-1,2,3-triazole 

Relevant academic research and scientific papers

Selective Synthesis of Functionally Substituted 1,2,3-Triazoles

Abstract: Different conditions were used to achieve selective formation of4.5-disubstituted 1-aryl(hetaryl)-1,2,3-triazoles via cycloaddition of thecorresponding enolates and aryl or hetaryl azides. Optimal conditions were foundfor the bromination of 1-(5

Design and synthesis of a novel class of carbonic anhydrase-IX inhibitor 1-(3-(phenyl/4-fluorophenyl)-7-imino-3H-[1,2,3]triazolo[4,5d]pyrimidin 6(7H)yl)urea

Carbonic anhydrase IX (CAIX) is a promising target in cancer therapy especially in the case of hypoxia-induced tumors. The selective inhibition of CA isozymes is a challenging task in drug design and discovery process. Here, we performed fluorescence-bind