203192-27-2Relevant academic research and scientific papers
Convenient one-pot synthesis of N,N′-bis(2-mercaptophenyl)pyridine-2,6-dicarboxamide and N-2-mercaptophenyl-2′-pyridinecarboxamide without protection of the thiol group(s)
Harrop, Todd C.,Rodriguez, Karina,Mascharak, Pradip K.
, p. 1943 - 1949 (2003)
A rapid and convenient procedure for the synthesis of N,N′-bis(2-mercaptophenyl)pyridine-2,6-dicarboxamide and N-2-mercaptophenyl-2′-pyridinecarboxamide from 2-aminothiophenol and the appropriate acid chloride is reported. The method is compatible only with aromatic acid chlorides containing a heteroatom. Aromatic acid chlorides with no heteroatom yield the corresponding 2-substituted benzothiazoles.
