20321-71-5

Upstream product

• 6250-88-0 4,9-Dihydropyrano<3,4-b>indol-1(3H)-on 

Downstream Products

• 77903-75-4 2-<2-(1-Cyanoethyl)-1H-indol-3-yl>ethyl p-toluenesulfonate 
• 77903-83-4 N-<2-<2-(1-Cyanoethyl)-1H-indol-3-yl>ethyl>-3-ethylpyridinium p-toluenesulfonate hemihydrate 
• 77903-81-2 N-<2-<2-(1-Cyanoethyl)-1H-indol-3-yl>ethyl>-3-cyanopyridinium p-toluenesulfonate hemihydrate 
• 77903-92-5 N-<2-<2-(1-Cyanoethenyl)-1H-indol-3-yl>ethyl>-3-(carbomethoxy)pyridinium p-toluenesulfonate monohydrate 
• 77903-79-8 N-<2-<2-(1-Cyanoethyl)-1H-indol-3-yl>ethyl>-3-(carbomethoxy)pyridinium p-toluenesulfonate hemihydrate 
• 77903-77-6 N-<2-<2-(1-Cyanoethyl)-1H-indol-3-yl>ethyl>-3,5-bis(carbomethoxy)pyridinium p-toluenesulfonate 

Relevant academic research and scientific papers

Synthesis and Chemistry of a Stabilized Dehydrosecodine Model System.

A stabilized dehydrosecodine analogue bearing carbomethoxy groups in the 3- and 5-positions of the dihydropyridine moiety has been prepared and its chemistry studied.Two novel procedures have been developed for this synthesis: (1) the Lewis acid assisted cleavage of an activated indole ether with trimethylsilylcyanide to form a cyano alcohol and (2) the oxidation of 2-(α-substituted ethyl)indoles with tert-butyl hypochlorite to form the corresponding 2-vinylindole derivatives.Thermal decomposition of the dehydrosecodine analogue does not yield the desired intramole-cular Diels-Alder adducts but instead seems to proceed by an intramolecular hydride transfer from the 1,2-dihydropyridine moiety to the vinylindole group.