77903-75-4

Upstream product

• 526-55-6 2-(3-indole)-ethanol 
• 20321-71-5 2-Acetyl-3-(2-hydroxyethyl)-1H-indole 
• 6250-88-0 4,9-Dihydropyrano<3,4-b>indol-1(3H)-on 
• 77903-96-9 3-(2-Hydroxyethyl)-1H-indole-2-carboxylic acid 
• 77903-73-2 3-(2-(vinyloxy)ethyl)-1H-indole 
• 77903-74-3 1-Methyl-1,3,4,9-tetrahydropyrano<3,4b>indole 
• 77924-76-6 2-<1-(Dimethylamino)ethyl>-3-(2-hydroxyethyl)-1H-indole 
• 77903-71-0 2-Ethyl-3-<2-(tert-butyldimethylsiloxy)ethyl>-1H-indole 
• 77903-97-0 <1-<3-(2-Hydroxyethyl)-1H-indol-2-yl>ethyl>trimethylammonium iodide 
• 76507-86-3 2-Ethyl-3-(2-hydroxyethyl)-1H-indole 

Downstream Products

• 77903-81-2 N-<2-<2-(1-Cyanoethyl)-1H-indol-3-yl>ethyl>-3-cyanopyridinium p-toluenesulfonate hemihydrate 
• 77903-79-8 N-<2-<2-(1-Cyanoethyl)-1H-indol-3-yl>ethyl>-3-(carbomethoxy)pyridinium p-toluenesulfonate hemihydrate 
• 77903-77-6 N-<2-<2-(1-Cyanoethyl)-1H-indol-3-yl>ethyl>-3,5-bis(carbomethoxy)pyridinium p-toluenesulfonate 
• 77903-92-5 N-<2-<2-(1-Cyanoethenyl)-1H-indol-3-yl>ethyl>-3-(carbomethoxy)pyridinium p-toluenesulfonate monohydrate 

Relevant academic research and scientific papers

Synthesis and Chemistry of a Stabilized Dehydrosecodine Model System.

A stabilized dehydrosecodine analogue bearing carbomethoxy groups in the 3- and 5-positions of the dihydropyridine moiety has been prepared and its chemistry studied.Two novel procedures have been developed for this synthesis: (1) the Lewis acid assisted cleavage of an activated indole ether with trimethylsilylcyanide to form a cyano alcohol and (2) the oxidation of 2-(α-substituted ethyl)indoles with tert-butyl hypochlorite to form the corresponding 2-vinylindole derivatives.Thermal decomposition of the dehydrosecodine analogue does not yield the desired intramole-cular Diels-Alder adducts but instead seems to proceed by an intramolecular hydride transfer from the 1,2-dihydropyridine moiety to the vinylindole group.