203259-05-6

Basic information

• Product Name: N-Benzoyl-N'-{1-[(2R,4S,5R)-4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-2-oxo-1,2-dihydro-pyrimidin-4-yl}-guanidine
• Synonyms: N-Benzoyl-N'-{1-[(2R,4S,5R)-4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-2-oxo-1,2-dihydro-pyrimidin-4-yl}-guanidine
• CAS NO: 203259-05-6
• Molecular Weight: 601.894
• Mol File: 203259-05-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-Benzoyl-N'-{1-[(2R,4S,5R)-4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-2-oxo-1,2-dihydro-pyrimidin-4-yl}-guanidine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Benzoyl-N'-{1-[(2R,4S,5R)-4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-2-oxo-1,2-dihydro-pyrimidin-4-yl}-guanidine(203259-05-6)
• EPA Substance Registry System: N-Benzoyl-N'-{1-[(2R,4S,5R)-4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-2-oxo-1,2-dihydro-pyrimidin-4-yl}-guanidine(203259-05-6)

Safety Data

• Hazardous Substances Data: 203259-05-6(Hazardous Substances Data)

Upstream product

• 51549-29-2 2'-deoxy-3',5'-bis-O-(tert-butyldimethylsilyl)cytidine 
• 532-55-8 Benzoyl isothiocyanate 
• 203259-04-5 1-Benzoyl-3-{1-[(2R,4S,5R)-4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-2-oxo-1,2-dihydro-pyrimidin-4-yl}-thiourea 

Relevant articles and documents

Synthesis of 4-guanidinopyrimidine nucleosides for triple helix-mediated guanine and cytosine recognition

Recognition of DNA sequences by triple helix-forming oligonucleotides is restricted to homopurine sequences. Based on geometrical considerations, a single nucleoside, 4-guanidinocytidine 1, was designed to recognize both guanosine (as the natural 1β anomer) and cytidine (as the 1α anomer) in a new triple helix context where the third strand is centered in the major groove of the target duplex. Several methods of synthesis of this nucleoside are described.