20330-92-1 Usage
Uses
Used in Pharmaceutical Industry:
3-chloro-N-(4-ethylphenyl)propanamide is utilized as a key intermediate in the synthesis of pharmaceuticals. Its unique structural features allow it to serve as a precursor to a variety of medicinally relevant compounds, contributing to the development of new drugs and therapeutic agents.
Used in Organic Chemistry:
In the realm of organic chemistry, 3-chloro-N-(4-ethylphenyl)propanamide is employed as a versatile building block. Its reactivity and structural attributes make it suitable for use in the creation of a wide array of organic compounds, facilitating advancements in chemical research and applications.
Safety Considerations:
Given its potential for irritant and harmful effects, 3-chloro-N-(4-ethylphenyl)propanamide should be handled and stored according to standard chemical safety protocols. Proper management is crucial to mitigate risks associated with its use in research and industrial settings.
Check Digit Verification of cas no
The CAS Registry Mumber 20330-92-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,3,3 and 0 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 20330-92:
(7*2)+(6*0)+(5*3)+(4*3)+(3*0)+(2*9)+(1*2)=61
61 % 10 = 1
So 20330-92-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H14ClNO/c1-2-9-3-5-10(6-4-9)13-11(14)7-8-12/h3-6H,2,7-8H2,1H3,(H,13,14)
20330-92-1Relevant academic research and scientific papers
Synthesis, in silico Study and Antileishmanial Evaluation of New Selenides Derived from 7-Chloro-quinoline and N-Phenylacetamides
Huang, Min-Fu N.,Luis, José A.S.,da Silva, Alison P.,Rocha, Juliana C.,Lima, Tatjana K.S.,Scotti, Marcus T.,Scotti, Luciana,de Oliveira, Rafael F.,Souza, Helivaldo D.S.,de Athayde-Filho, Petr?nio F.,Barbosa-Filho, José M.
, p. 712 - 721 (2021/03/17)
This study describes a virtual screening performed for two series of selenides (28 compounds), derived from N-phenylacetamides chlorides and 7-chloro-quinoline, to determine their potential for leishmanicidal activity against Leishmania amazonensis and Leishmania donovani. Seven compounds were predicted as potential leishmanicides; therefore, they were synthesized from elemental selenium, as a precursor for the production of NaHSe, and subsequent reactions with 4,7-dichloro-quinoline and N-phenylacetamides chlorides were performed. The compounds were characterized by infrared (IR), 1H and 13C nuclear magnetic resonance (NMR), and sent for in vitro cytotoxicity tests against L. amazonensis and were found to be active and selective, and two compounds presented half-maximal inhibitory concentrations (IC50) of 5.67 and 10.81 μg mL-1. They also presented good interaction energies in the docking study, suggesting that may exert their effects by inhibiting the N-myristoyltransferase and O-acetylserine sulfhydrylase enzymes in parasites.
