203302-74-3

Basic information

• Product Name: 1H-Benzimidazol-5-amine,2-chloro-1-methyl-(9CI)
• Synonyms: 1H-Benzimidazol-5-amine,2-chloro-1-methyl-(9CI)
• CAS NO: 203302-74-3
• Molecular Formula: C₈H₈ClN₃
• Molecular Weight: 181.625
• Product Categories: BENZIMIDAZOLE
• Mol File: 203302-74-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Benzimidazol-5-amine,2-chloro-1-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazol-5-amine,2-chloro-1-methyl-(9CI)(203302-74-3)
• EPA Substance Registry System: 1H-Benzimidazol-5-amine,2-chloro-1-methyl-(9CI)(203302-74-3)

Safety Data

• Hazardous Substances Data: 203302-74-3(Hazardous Substances Data)

Usage

Derivative of benzimidazole

Heterocyclic compound with a fused benzene and imidazole ring system

Uses

Synthesis of pharmaceuticals and agrochemicals

Biological activities

Antitumor, antiviral, and anti-inflammatory properties

Pest control applications

Insecticidal and fungicidal activities

Research interest

Medicinal chemistry, agriculture, and pharmaceutical development

Upstream product

• 15965-67-0 2-chloro-1-methyl-6-nitro-1H-benzoimidazole 
• 15965-66-9 2-chloro-1-methyl-5-nitro-1H-benzoimidazole 
• 5955-72-6 2-chloro-5-nitro-1H-benzo[d]imidazole 
• 74-88-4 methyl iodide 
• 1849-02-1 2-chloro-1-methyl-benzimidazole 
• 4857-06-1 2-chloro-1H-benzoimidazole 

Downstream Products

• 950778-39-9 2-chloro-1-methyl-4-nitro-1H-benzoimidazol-5-ylamine 
• 850172-50-8 N-(2-chloro-1-methyl-1H-benzimidazol-6-yl)-2-(4-trifluoromethylphenoxy)acetamide 
• 850172-51-9 N-(2-chloro-1-methyl-1H-benzimidazol-5-yl)-2-(4-trifluoromethylphenoxy)acetamide 
• 203302-77-6 N-[(2-chloro-1-methyl-1H-benzimidazol-5-yl)amino]benzoic acid 

Relevant articles and documents

Synthesis of benzo[1,2-d;3,4-d′]diimidazole and 1H-pyrazolo[4,3-b] pyridine as putative A2A receptor antagonists

The synthesis and the binding affinity for the putative adenosine receptor antagonist 6-methyl-7-[1,2,3]triazol-2-yl-1,6-dihydrobenzo[1,2-d;3,4-d′] diimidazole (10) and 5-oxazol-2-yl-1H-pyrazolo[4,3-b]pyridin-3-ylamine (16) are reported. The title compounds were prepared from commercially available 1-chloro-2,4-dinitrobenzene (1) and 2-chloro-6-methoxy-3nitropyridine (11), respectively, but proved devoid of affinity for the adenosine A1 and A2A receptors. The Royal Society of Chemistry.

BICYCLIC COMPOUNDS AND THEIR THERAPEUTIC USE

Compounds of the formula (1) are useful as MCH mediator, and in the therapy of obesity.