15965-66-9

Basic information

• Product Name: 2-CHLORO-1-METHYL-5-NITRO-1H-BENZO[D]IMIDAZOLE
• Synonyms: 2-CHLORO-1-METHYL-5-NITRO-1H-BENZO[D]IMIDAZOLE;2-Chloro-1-methyl-5-nitro-1H-1,3-benzodiazole
• CAS NO: 15965-66-9
• Molecular Formula: C₈H₆ClN₃O₂
• Molecular Weight: 211.61
• Mol File: 15965-66-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 184-185 °C
• Boiling Point: 402.0±37.0 °C(Predicted)
• Appearance: /
• Density: 1.58±0.1 g/cm3(Predicted)
• PKA: 1.85±0.10(Predicted)
• CAS DataBase Reference: 2-CHLORO-1-METHYL-5-NITRO-1H-BENZO[D]IMIDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-1-METHYL-5-NITRO-1H-BENZO[D]IMIDAZOLE(15965-66-9)
• EPA Substance Registry System: 2-CHLORO-1-METHYL-5-NITRO-1H-BENZO[D]IMIDAZOLE(15965-66-9)

Safety Data

• Hazardous Substances Data: 15965-66-9(Hazardous Substances Data)

Upstream product

• 5955-72-6 2-chloro-5-nitro-1H-benzo[d]imidazole 
• 74-88-4 methyl iodide 
• 596131-59-8 1-methyl-5-nitro-1,3-dihydro-benzimidazole-2-thione 
• 41939-61-1 N₁-methyl-4-nitrobenzene-1,2-diamine 
• 21395-42-6 3-acetyl-1-methyl-5-nitro-1,3-dihydro-benzoimidazol-2-one 
• 4857-06-1 2-chloro-1H-benzoimidazole 
• 5381-78-2 1-methyl-5-nitro-1H-benzo[d]imidazole 
• 10026-13-8 phosphorus pentachloride 
• 66108-85-8 1-methyl-5-nitro-1,3-dihydro-2H-benzo[d]imidazol-2-one 
• 10025-87-3 trichlorophosphate 

Downstream Products

• 203302-74-3 2-chloro-1-methyl-1H-benzoimidazol-5-ylamine 
• 203302-75-4 6-amino-2-chloro-1-methyl-1H-benzimidazole 

Relevant articles and documents

Synthesis of benzo[1,2-d;3,4-d′]diimidazole and 1H-pyrazolo[4,3-b] pyridine as putative A2A receptor antagonists

The synthesis and the binding affinity for the putative adenosine receptor antagonist 6-methyl-7-[1,2,3]triazol-2-yl-1,6-dihydrobenzo[1,2-d;3,4-d′] diimidazole (10) and 5-oxazol-2-yl-1H-pyrazolo[4,3-b]pyridin-3-ylamine (16) are reported. The title compounds were prepared from commercially available 1-chloro-2,4-dinitrobenzene (1) and 2-chloro-6-methoxy-3nitropyridine (11), respectively, but proved devoid of affinity for the adenosine A1 and A2A receptors. The Royal Society of Chemistry.

DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS

Benzimidazole derivatives of formula (I) , which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such benzimidazole derivatives as well as methods of using the same in the treatme

Pyridinium Betaines Derived from Thiazolo and Imidazoacridinones

Four betaines derived from imidazo[4,5-a], imidazo[5,4-a] and thiazolo[5,4-a]acridine have been prepared in a six step procedure starting from 2-chlorobenzimidazoles and benzothiazoles. The 1H and 133C nmr has been used to characteri