203321-83-9Relevant academic research and scientific papers
Efficient synthesis of tert-Butyl (6-Formylpyridin-2-yl)carbamic acid
Majgier-Baranowska, Helena,Li, Bing,Peet, Norton P.
, p. 1173 - 1180 (2013)
We have developed an efficient four-step synthesis of tert-butyl (6-formylpyridin-2-yl)carbamic acid (1) in 80% overall yield using inexpensive starting material and reagents and no air-sensitive reagents. Column chromatography was not required for purification of the intermediates or the final product.
POLY HETEROCYCLIC CONJUGATES AND THEIR PHARMACEUTICAL USES
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Paragraph 0039-0040; 0043, (2022/01/04)
Compounds of Formula (I) shown below and a pharmaceutical composition containing one of the compounds: Each of the variables is defined herein. Also disclosed is a method of treating a condition associated with uncontrolled cell growth with a compound of Formula (I).
Phenyl oxime derivative and preparation method and application thereof
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Paragraph 0113-0114, (2020/12/31)
The invention relates to a phenyl oxime derivative as well as a preparation method and application thereof. Specifically, the present invention relates to a phenyl oxime derivative represented by formula (I) or a stereoisomer of the phenyl oxime derivativ
THIOBENZOIMIDAZOLE AS FUNGICIDES
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Page/Page column 65; 75, (2018/08/03)
The present invention relates to 2-thiobenzimidazoles of formula (I) which are of use as fungicides.
AGRICULTURAL CHEMICALS
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, (2017/11/10)
The present invention relates to compounds which are of use in the field of agriculture as fungicides.
SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS
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Paragraph 0778; 0779, (2017/04/04)
Provided herein are novel substituted bicyclic aza-heterocycle sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.
QUINOLINES AND RELATED ANALOGS AS SIRTUIN MODULATORS
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Paragraph 0360; 0361, (2016/08/17)
Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.
An affinity reagent for the recognition of pyrophosphorylated peptides
Conway, John H.,Fiedler, Dorothea
supporting information, p. 3941 - 3945 (2015/03/30)
A resin-bound dinuclear zinc(II) complex for the selective capture of pyrophosphopeptides is reported. The metal complex binds diphosphate esters over other anionic groups, such as monophosphate esters, sulfate esters, and carboxylic acids, with high spec
2-PYRIDYL CARBOXAMIDE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS
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Paragraph 00210, (2013/04/24)
The invention provides certain 2-pyridyl carboxamide-containing compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein A and B are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.
SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS
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Page/Page column 196, (2013/05/09)
Provided herein are novel substituted bicyclic aza-heterocycle sirtuin- modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin- modulating compound in combination with another therapeutic agent.
