20333-73-7

Basic information

• Product Name: Thiourea, N-(4-methoxyphenyl)-N'-methyl-
• CAS NO: 20333-73-7
• Molecular Formula: C9H12N2OS
• Molecular Weight: 196.273
• Mol File: 20333-73-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Thiourea, N-(4-methoxyphenyl)-N'-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiourea, N-(4-methoxyphenyl)-N'-methyl-(20333-73-7)
• EPA Substance Registry System: Thiourea, N-(4-methoxyphenyl)-N'-methyl-(20333-73-7)

Safety Data

• Hazardous Substances Data: 20333-73-7(Hazardous Substances Data)

Upstream product

• 104-94-9 4-methoxy-aniline 
• 556-61-6 methyl thioisocyanate 
• 2284-20-0 4-Methoxyphenyl isothiocyanate 
• 74-89-5 methylamine 
• 75390-41-9 Tetra-p-anisidyl-oxalamidin 

Downstream Products

• 1628629-66-2 5-(2-hydroxyphenyl)-3-methyl-2-[(4-methoxyphenyl)imino]-1,3-thiazolidin-4-one 
• 1628629-82-2 N-methyl-N'-(4-methoxyphenyl)-S-(2-oxo-2,3-dihydro-1-benzofuran-3-yl)isothiuronium bromide 
• 1019107-89-1 3-(4-methoxyphenyl)-1-methyl-5-[(E)-1-phenylmethylidene]-2-thioxoimidazolidin-4-one 
• 1019107-90-4 1-(4-methoxyphenyl)-3-methyl-5-[(E)-1-phenylmethylidene]-2-thioxoimidazolidin-4-one 
• 68454-60-4 2,4-Dimethyl-3,5-bis-(p-methoxyphenylimino)-1,2,4-thiadiazolidin 
• 58432-34-1 N-(4-methoxy-phenyl)-N',S-dimethyl-isothiourea 
• 51661-22-4 6-methoxy-2-methylaminobenzothiazole 

Relevant articles and documents

Nickle Catalysis Enables Access to Thiazolidines from Thioureas via Oxidative Double Isocyanide Insertion Reactions

An efficient synthesis of thiazolidine-2,4,5-triimine derivatives was developed via Ni-catalyzed oxidative double isocyanide insertion to thioureas under air conditions, in which thioureas play three roles as a substrate, a ligand, and overcoming isocyanide polymerization. The reaction is featured by employing a low-cost and low loading Ni(acac)2 catalyst, without any additives, and high atom economy. This is the first example to directly apply a Ni(II) catalyst in oxidative double isocyanide insertion reactions.

Quantitative solid-state reactions of amines with carbonyl compounds and isothiocyanates

A series of solid-state reactions is reported of gaseous or solid amines with aldehydes to give imines, with solid anhydrides to give diamides (therefrom imides) or amidic carboxylic salts or imides, with solid imides to give diamides, with solid lactones or carbonates to give functionalized carbamic esters, with polycarbonates to give degradative aminolysis, and with solid isothiocyanates to give thioureas. Diamides give imides by solid-state thermolysis or acid catalysis. Various double, two-step, 3-cascade, and sequential reactions are reported in the solid state without melting. The yields are quantitative in 53 reported reaction examples and no workup (except for washings in four cases) is required in the 100% yield reactions. Three initially solid-state reactions but with liquid product were not quantitative. An upscaling to the kg scale shows promise of the technique for large scale applications. Supermicroscopic analyses with AFM elucidate the solid-state mechanism by virtue of far-reaching anisotropic molecular movements in three-step processes. Gas-solid aminolyses of polycarbonates are also studied with AFM. The implications to sustainable chemistry are discussed. (C) 2000 Elsevier Science Ltd.

Derivatives of Imidazolidines from Oxalic Amidines

Tetraarylsubstituted oxalic amidines 1 react with acyl chlorides, phosgene, thiophosgene, chlorocarbonylsulfenylchloride, isocyaniddichlorides, and N-aroyl-1-chlorothio-formimidoylchlorides 7 to give the corresponding 5-membered heterocycles 3,4,5 and 8.Isocyanates 9 and isothiocyanates 10 react with oxalic amidines to yield imidazolidines 11, 12 and ureas 13, 14.Hydrolysis of 3-5, 8, 11, 12 leads to the corresponding oxo compounds 15, 16.