203385-15-3

Usage

Uses

Used in Pharmaceutical Industry:
2-(2-CHLORO-ACETYLAMINO)-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER is used as a potential pharmaceutical agent for its possible biological activity, which may be explored for therapeutic applications, including the development of new drugs or drug candidates.
Used in Organic Synthesis:
In the field of organic synthesis, 2-(2-CHLORO-ACETYLAMINO)-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER serves as a precursor for the synthesis of other complex organic molecules, contributing to the creation of novel chemical entities with potential applications in various industries.
Used in Organic Chemistry Research:
As a research tool in organic chemistry, 2-(2-CHLORO-ACETYLAMINO)-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER is utilized to study its reactivity, properties, and potential interactions with other molecules, aiding in the advancement of chemical knowledge and the discovery of new reaction pathways or mechanisms.

InChI:InChI=1/C12H14ClNO3S/c1-2-17-12(16)10-7-4-3-5-8(7)18-11(10)14-9(15)6-13/h2-6H2,1H3,(H,14,15)

Upstream product

• 4815-29-6 ethyl 2-amino-4H,5H,6H-cyclopentenothiophene-3-carboxylate 
• 79-04-9 chloroacetyl chloride 
• 105-56-6 ethyl 2-cyanoacetate 
• 120-92-3 cyclopentanone 

Downstream Products

• 307343-77-7 ethyl 2-(2-(3-allyl-3,4-dihydro-4-oxo-5-phenylthieno[2,3-d]pyrimidin-2-ylthio)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate 

Relevant academic research and scientific papers

Synthesis and analgesic activities of some 2-(benzazolylacetyl)amino-3- ethoxycarbonylthiophene derivatives

In this study, some 2-[2-(benzazole-2-thioxy)acetylamino]-3- ethoxycarbonylthiophene and 2-[2-(benzazole-1-yl)acetylamino]-3- ethoxycarbonylthiophene compounds were obtained by the reaction of 2-chloroacetylamino-3-ethoxycarbonylthiophene derivatives and a suitable benzazole-2-thione or benzimidazole derivatives. Analgesic activities of the compounds were tested by using tail-flick and tail-immersion methods. It is reported that some of the compounds showed remarkable analgesic activities. Copyright Taylor & Francis Inc.

Substituted chloroacetamides as potential cancer stem cell inhibitors: Synthesis and biological evaluation

Cancer kills, irrespective of geographical and cultural origin. Novel modalities for treating cancer are desperately needed. Cancer stem cells (CSCs), main culprits behind chemoresistance and tumor relapse, are one of the few logical choices. Herein, we r

2-(3,4-dihydro-4-oxothieno[2,3-d]pyrimidin-2-ylthio) acetamides as a new class of falcipain-2 inhibitors. 3. design, synthesis and biological evaluation

The cysteine protease falcipain-2 (FP-2) of Plasmodium falciparum is a principal cysteine protease and an essential hemoglobinase of erythrocytic P. falciparum trophozoites, making it become an attractive target enzyme for developing anti-malarial drugs.

ANTHELMINTIC AND INSECTICIDAL THIOPHENE DERIVATIVES

Novel anthelmintic compositions containing thiophene derivatives as active ingredients are disclosed.

Synthesis and biological evaluation of new cyclopenteno[b]thiophene derivatives as local anesthetic and antiarrhythmic agents

A series of ethyl 2-substituted amino-cyclopenteno[b]thiophen-3-carboxylates was synthesized as a carticaine analogues and evaluated for their local anesthetic and antiarrhythmic activity. Compounds ethyl 2-[1-oxo-2-(ethylamino)ethylamino]- (4a), ethyl 2-