203387-36-4Relevant academic research and scientific papers
Stereoselective total synthesis of C2-symmetric natural products pyrenophorol and its derivatives
Narala, Siva Ganesh,Nagalatha,Venkat Narsaiah
supporting information, p. 2173 - 2178 (2019/03/11)
A stereoselective total synthesis of 16-membered C2-symmetric macrodiolide Pyrenophorol, Tetrahydropyrenophorol and 4,4-diacetylpyrenophorol have been accomplished. The synthesis started from commercially available L-Aspartic acid and the key reactions involved are regioselective epoxide opening, CBS reduction, Pinnick oxidation and Mitsunobu dilactonization.
A chemoenzymatic synthesis of hept-6-ene-2,5-diol stereomers: Application to asymmetric synthesis of decarestrictine L, pyrenophorol, and stagonolide e
Chatterjee, Sucheta,Ghadigaonkar, Sneha,Sur, Payel,Sharma, Anubha,Chattopadhyay, Subrata
, p. 8067 - 8076 (2015/03/18)
The stereomers of hept-6-ene-2,5-diol derivatives were conceived as useful chiral intermediates and were synthesized starting from sulcatol using two lipase-catalyzed acylation reactions as the key steps. The versatility of the intermediates was demonstrated by converting them to the titled tetrahydropyran, macrolide, and macrodiolide compounds using standard synthetic protocols.
Total synthesis of (-)-pyrenophorol
Yadav, Jhillu S.,Reddy, Ganapuram Madhusudhan,Rao, Tenneti Srinivasa,Reddy, Basi V. Subba,Al Khazim Al Ghamdi, Ahmad
, p. 783 - 787 (2012/04/10)
An efficient synthetic route has been developed for the synthesis of (-)-pyrenophorol employing Sharpless asymmetric epoxidation, olefin cross-metathesis, and intermolecular Mitsunobu cyclization. Georg Thieme Verlag Stuttgart · New York.
A concise asymmetric route to the antibiotic macrolides patulolide A and pyrenophorin
Rao, K. Srinivasa,Reddy, D. Srinivasa,Mukkanti,Pal, Manojit,Iqbal, Javed
, p. 6623 - 6626 (2007/10/03)
In this letter, we describe an enantiospecific route to patulolide A and pyrenophorin through the synthesis of known protected seco acid precursors starting from commercially available (S)-ethyl lactate.
Total Synthesis of the Boron-Containing Ion Carrier Antibiotic Macrodiolide Tartrolon B
Mulzer, Johann,Berger, Markus
, p. 891 - 898 (2007/10/03)
The first total synthesis of the boron-containing macrodiolide antibiotic tartrolon B is reported in full detail. Two convergent approaches to the target compound are described, the first of which eventually failed, due to sensitive functionality. In the
Studies directed towards the total synthesis of the antibiotic macrodiolide tartrolon: EPC synthesis of the protected seco acid
Mulzer, Johann,Berger, Markus
, p. 803 - 806 (2007/10/03)
An efficient synthesis of the protected seco acid 2 of the antibiotic macrodiolide tartrolon 1 is described. Key steps are a substrate controlled aldol-reaction, a Johnson-Claisen rearrangement, and a Horner-Wadsworth-Emmons olefination with subsequent Co
