203387-47-7

Upstream product

• 90472-93-8 methyl 3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]propanoate 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 
• 203387-51-3 ethyl (4S)-4-(tert-butyl(diphenyl)silyloxy)pentanoate 
• 203387-35-3 (E)-(S)-4-(tert-butyl-diphenyl-silanyloxy)-pent-2-enoic acid ethyl ester 
• 203387-36-4 (4S)-4-(tert-butyl(diphenyl)silyloxy)pentanal 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 42890-81-3 (4S)-4,5-(isopropylidenedioxy)-1-pentanal 
• 102732-44-5 ethyl (S)-2-(tert-butyldiphenylsilyloxy)propanoate 
• 87696-33-1 (S)-2-(O-tert-butyldiphenylsilyloxy)propanal 
• 81703-93-7 methyl (2E)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]acrylate 
• 203387-46-6 (1E,5S)-1-iodo-5,6-(isopropylidenedioxy)hex-1-ene 
• 203387-37-5 (5S)-5-(tert-butyl(diphenyl)silyloxy)-1-hexyne 

Downstream Products

• 203387-32-0 methyl (4R,7S,8S,11S,14E,16Z,20S)-20-(tert-butyl(diphenyl)silyloxy)-4,8-dimethyl-3,9-dioxo-2,7,11-tri-(p-methoxybenzyloxy)-unicosa-14,16-dienoate 
• 668461-38-9 methyl (4R,7S,8S,11S,14E,16Z,20S)-20-(tert-butyl(diphenyl)silyloxy)-4,8-dimethyl-9-oxo-2,7,11-tri-(p-methoxybenzyloxy)-unicosa-14,16-dienoate 
• 668461-36-7 (2R,5S,6S,9S,12E,14Z,18S)-1-(tert-butyl(dimethyl)silyloxy)-18-(tert-butyl(diphenyl)silyloxy)-2,6-dimethyl-5,9-di-(p-methoxybenzyloxy)-nonadeca-12,14-dien-7-one 
• 668461-37-8 (2R,5S,6S,9S,12E,14Z,18S)-18-(tert-butyl(diphenyl)silyloxy)-2,6-dimethyl-5,9-di-(p-methoxybenzyloxy)-1-hydroxynonadeca-12,14-dien-7-one 
• 203387-54-6 (2R,5S,6S,9S,12E,14Z,18S)-18-(tert-butyl(diphenyl)silyloxy)-2,6-dimethyl-5,9-di-(p-methoxybenzyloxy)-7-oxo-nonadeca-12,14-dienal 
• 203387-50-2 (2R,5S,6S,9S,12E,14Z,18S)-1-(tert-butyl(dimethyl)silyloxy)-18-(tert-butyl(diphenyl)silyloxy)-2,6-dimethyl-9-hydroxy-5-(p-methoxybenzyloxy)-7,7-(propan-1',3'-dithio)nonadeca-12,14-diene 
• 203387-45-5 (12E,14Z)-(2R,5S,6S,9S,18S)-1-(tert-Butyl-dimethyl-silanyloxy)-18-(tert-butyl-diphenyl-silanyloxy)-9-hydroxy-5-(4-methoxy-benzyloxy)-2,6-dimethyl-nonadeca-12,14-dien-7-one 
• 203387-48-8 tert-Butyl-((4Z,6E)-(S)-1-methyl-9-(S)-oxiranyl-nona-4,6-dienyloxy)-diphenyl-silane 

Relevant academic research and scientific papers

Studies directed towards the total synthesis of the antibiotic macrodiolide tartrolon: EPC synthesis of the protected seco acid

An efficient synthesis of the protected seco acid 2 of the antibiotic macrodiolide tartrolon 1 is described. Key steps are a substrate controlled aldol-reaction, a Johnson-Claisen rearrangement, and a Horner-Wadsworth-Emmons olefination with subsequent Co