203436-18-4

Upstream product

• 100-39-0 benzyl bromide 
• 203436-09-3 2-chloro-N-(4-methoxybenzyl)-9H-purin-6-amine 
• 2393-23-9 4-methoxy-benzylamine 
• 5451-40-1 2,6 dichloropurine 

Downstream Products

• 1007555-57-8 C₂₁H₁₈N₆O 
• 56046-25-4 6-amino-9-benzyl-2-chloropurine 

Relevant academic research and scientific papers

COMPOUNDS FOR TREATING CYSTIC FIBROSIS

The present invention relates to compounds of Formula (I) or pharmaceutically acceptable enantiomers, salts, solvates or prodrugs thereof. The invention further relates to the use of the compounds of Formula (I) for the treatment of cystic fibrosis. The invention also relates to a process for manufacturing compounds of Formula (I).

Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB

Human African trypanosomiasis (HAT), a major health concern in sub-Saharan Africa, is caused by the protozoan parasite Trypanosoma brucei. Recent studies have shown that a cathepsin B like protease, TbcatB, is essential to the survival of T. brucei in vit