203436-33-3Relevant articles and documents
Pyrimido five-membered heterocyclic compound and application as mutant IDH2 inhibitor
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Paragraph 0123-0127, (2020/11/11)
The invention relates to a pyrimido five-membered heterocyclic compound and an application of the pyrimido five-membered heterocyclic compound as a mutant IDH2 inhibitor, and specifically discloses apyrimido five-membered heterocyclic compound capable of being used as a mutant IDH2 inhibitor, or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt, a hydrate or a solvate thereof. The invention also relates to a pharmaceutical composition containing the compound, and application of the pharmaceutical composition in preparation of drugs for preventing and/or treating mutantIDH2 mediated diseases.
Purine inhibitors of cyclin dependent kinase 2
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, (2008/06/13)
A 2,6,9-trisubstituted purine composition having the following formula: STR1 where X is a amino, oxo, thio, of sulfone moiety, R1 is a lower alkyl, substituted lower alkyl, cycloalkyl, substituted cycloalkyl, cycloheteroalkyl, substituted cyclo