20357-06-6

Basic information

• Product Name: 3-(4-methyl-2-nitrophenyl) propynoic acid
• Synonyms: 3-(4-methyl-2-nitrophenyl) propynoic acid
• CAS NO: 20357-06-6
• Molecular Weight: 205.17
• Mol File: 20357-06-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(4-methyl-2-nitrophenyl) propynoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-methyl-2-nitrophenyl) propynoic acid(20357-06-6)
• EPA Substance Registry System: 3-(4-methyl-2-nitrophenyl) propynoic acid(20357-06-6)

Safety Data

• Hazardous Substances Data: 20357-06-6(Hazardous Substances Data)

Upstream product

• 5326-39-6 4-iodo-3-nitrotoluene 
• 124-38-9 carbon dioxide 
• 106851-21-2 4-methyl-2-nitro-1-[2-(trimethylsilyl)ethynyl]benzene 

Relevant articles and documents

Synthesis of Piperidinone and Azepanone Fused Indoles via a Wagner-Meerwein Type 1,2-Amide Migration of 2-Spiropseudoindoxyls

Spiropseudoindoxyls were synthesized by using a gold(III)-catalyzed intramolecular nitroalkyne redox-dipolar cycloaddition cascade. These compounds were then transformed into novel piperidinone and azepanone fused indoles via a straightforward hydrogenation. The reaction mechanism of this ring expansion is believed to proceed through a rare Wagner-Meerwein type 1,2-amide migration.