203587-54-6

Basic information

• Product Name: 5,7-Dimethyl-2-phenyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester
• Synonyms: 5,7-Dimethyl-2-phenyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester
• CAS NO: 203587-54-6
• Molecular Weight: 295.341
• Mol File: 203587-54-6.mol

Chemical Properties

• CAS DataBase Reference: 5,7-Dimethyl-2-phenyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5,7-Dimethyl-2-phenyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester(203587-54-6)
• EPA Substance Registry System: 5,7-Dimethyl-2-phenyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester(203587-54-6)

Safety Data

• Hazardous Substances Data: 203587-54-6(Hazardous Substances Data)

Upstream product

• 1572-10-7 3⁽⁵⁾-phenylpyrazol-5⁽³⁾-amine 
• 603-69-0 ethyl 2-acetylacetoacetate 
• 827-41-8 3-phenylpyrazol-5-amine 

Downstream Products

• 739364-98-8 5,7-dimethyl-2-phenylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid 

Relevant articles and documents

COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV

The invention aims to provide a dipeptidyl peptidase IV inhibitor which is satisfactory in respect of activity, stability and safety and has an excellent action as a pharmaceutical agent. The invention is directed to a compound represented by the following general formula or a pharmaceutically acceptable salt thereof: wherein R1 and R2 each represents hydrogen, an optionally substituted C1-6 alkyl group, or -COOR5 whereupon R5 represents hydrogen or an optionally substituted C1-6 alkyl group, or R1 and R2, together with a carbon atom to which they are bound, represent a 3- to 6-membered cycloalkyl group, R3 represents hydrogen or an optionally substituted C6-10 aryl group, R4 represents a hydrogen or a cyano group, D represents -CONR6-, -CO- or -NR6CO-, R6 represents hydrogen or an optionally substituted C1-6 alkyl group, E represents -(CH2)m- whereupon m is an integer of 1 to 3, -CH2OCH2-, or -SCH2-, n is an integer of 0 to 3, and A represents an optionally substituted bicyclic heterocyclic group or bicyclic hydrocarbon group.

Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6-ones. II. Synthesis and in vitro antimicrobial evaluation

A series of pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6-ones (4a-p) was prepared by a simple synthetic procedure based on the reaction of hydroxylamine or methoxyamine with 2,3-substituted ethyl 7-dimethylaminovinyl pyrazolo[1,5-a]pyrimidin-6-carboxylates (3a