203663-25-6

Basic information

• Product Name: Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester
• Synonyms: Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester;tert-butyl 5-hydroxy-hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate;tert-butyl 5-hydroxy-octahydrocyclopenta[c]pyrrole-2-carboxylate;5-Hydroxyhexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester
• CAS NO: 203663-25-6
• Molecular Formula: C₁₂H₂₁NO₃
• Molecular Weight: 227.30004
• Mol File: 203663-25-6.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester(203663-25-6)
• EPA Substance Registry System: Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester(203663-25-6)

Safety Data

• Hazardous Substances Data: 203663-25-6(Hazardous Substances Data)

Usage

General Description

Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-hydroxy-, 1,1-diMethylethyl ester is a chemical compound commonly known as CP55,940. It is a synthetic cannabinoid that acts as a potent agonist at the cannabinoid receptors, particularly the CB1 receptor. CP55,940 is widely used in scientific research to study the effects of cannabinoid receptor activation on various physiological and neurological processes. It has been shown to have strong analgesic, anti-inflammatory, and neuroprotective properties, and it also exhibits potential for therapeutic use in conditions such as pain management, neurodegenerative diseases, and drug addiction. However, its psychoactive effects and potential for abuse also raise concerns about its safety and regulation.

Upstream product

• 148404-28-8 tert-butyl 5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate 
• 10533-30-9 2,3,3a,4,7,7a-hexahydro-1H-isoindole 
• 85-40-5 1,2,3,6-tertahydrophthalimide 

Downstream Products

• 1395322-86-7 2-(2-fluoro-4-nitrophenyl)-5-oxohexahydrocyclopenta[c]pyrrole 
• 1395322-87-8 2-(2-fluoro-4-nitrophenyl)-hexahydro-1H-spiro[cyclopenta[c]pyrrole-5,2'-[1,3]dioxolane] 
• 1395322-88-9 2-(4-amino-2-fluorophenyl)-hexahydro-1H-spiro[cyclopenta[c]pyrrole-5,2'-[1,3]dioxolane] 
• 1395322-90-3 (5R)-3-(3-fluoro-4-(tetrahydro-1H-spiro[cyclopenta[c]pyrrole-5,2'-[1,3]dioxolane]-2(3H)-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one 
• 1417820-60-0 2-[2-fluoro-4-[(5R)-5-[[(methylsulfonyl)oxy]methyl]-2-oxo-3-oxazolidinyl]phenyl]-hexahydro-1H-spiro[cyclopenta[c]pyrrole-5,2'-[1,3]dioxolane] 
• 1395322-91-4 (5R)-5-(azidomethyl)-3-(3-fluoro-4-(tetrahydro-1H-spiro[cyclopenta[c]pyrrole-5,2'-[1,3]dioxolane]-2(3H)-yl)phenyl)-oxazolidin-2-one 
• 1395322-92-5 N-(((5S)-3-(3-fluoro-4-(tetrahydro-1H-spiro[cyclopenta[c]pyrrole-5,2'-[1,3]dioxolane]-2(3H)-yl)phenyl)-2-oxo-oxazolidin-5-yl)methyl)acetamide 
• 1395322-93-6 (5R)-5-((1H-1,2,3-triazol-1-yl)methyl)-3-(3-fluoro-4-(tetrahydro-1H-spiro[cyclopenta[c]pyrrole-5,2'-[1,3]dioxolane]-2(3H)-yl)phenyl)oxazolidin-2-one 
• 1401464-09-2 2-[(tert-butoxy)carbonyl]-octahydrocyclopenta[c]pyrrole-5-carboxylic acid 

Relevant articles and documents

NOVEL INHIBITORS OF AUTOTAXIN

The present invention relates to novel heterocyclic compounds of general formula (I) and their pharmaceutically acceptable salts, enantiomers and their diastereomers that are autotaxin (ATX) inhibitors. Compounds of general formula (I), their pharmaceutically acceptable salts and pharmaceutical composition are useful for the treatment and prophylaxis of conditions or a disorder caused by autotaxin (ATX) activation or increased concentration of lysophosphatidic acid (LPA).

RET Inhibitor. Pharmaceutical composition and use thereof

The invention belongs to the field of medicines, and relates to RET inhibitor, a pharmaceutical composition and application thereof. , The present invention relates to a compound represented by formula (I), a stereoisomer, a tautomer, an oxynitride, a solvate, a metabolite, a pharmaceutically acceptable salt or prodrug thereof, I, and a pharmaceutical composition thereof in the manufacture of a medicament, in particular for the treatment and prophylaxis of diseases and disorders associated and RET.

THIENOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE

The present invention relates to a thienopyrimidine derivative and use thereof in medicine, and also to a pharmaceutical composition containing the compound. The compound or pharmaceutical composition is used for inhibiting acetyl-CoA carboxylase (ACC). The present invention also relates to a method of preparing such compound and pharmaceutical composition, as well as their use in the treatment or prevention of diseases regulated by acetyl-CoA carboxylase in mammals, especially in humans.