203719-99-7Relevant academic research and scientific papers
5-aminomethylquinoxaline-2,3-diones. Part 1: A novel class of ampa receptor antagonists.
Auberson, Yves P.,Bischoff, Serge,Moretti, Robert,Schmutz, Markus,Veenstra, Siem J.
, p. 65 - 70 (1998)
A series of 5-aminomethylquinoxaline-2,3-diones have been identified as potent and selective AMPA antagonists. Some of these compounds are also active at the glycine-binding site of the NMDA receptors. A number of these novel, water-soluble quinoxaline-2,3-dione derivatives display protective effects in the electroshock-induced convulsion model in mice.
