Bioorganic and Medicinal Chemistry Letters p. 65 - 70 (1998)
Update date:2022-09-26
Topics:
Auberson, Yves P.
Bischoff, Serge
Moretti, Robert
Schmutz, Markus
Veenstra, Siem J.
A series of 5-aminomethylquinoxaline-2,3-diones have been identified as potent and selective AMPA antagonists. Some of these compounds are also active at the glycine-binding site of the NMDA receptors. A number of these novel, water-soluble quinoxaline-2,3-dione derivatives display protective effects in the electroshock-induced convulsion model in mice.
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Doi:10.1080/00397919808005084
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(2002)Doi:10.1021/ja981635p
(1998)Doi:10.1055/s-2003-37118
(2003)Doi:10.1016/S0040-4020(98)00424-4
(1998)Doi:10.1021/ie50511a048
(1952)
