203792-23-8

Basic information

• Product Name: 1-[2-(tert-butoxycarbonyl-tert-butoxycarbonylmethyl-amino)-3-cyclohexyl-propionyl]-2,5-dihydro-1H-pyrrole-2-carboxylic acid
• Synonyms: 1-[2-(tert-butoxycarbonyl-tert-butoxycarbonylmethyl-amino)-3-cyclohexyl-propionyl]-2,5-dihydro-1H-pyrrole-2-carboxylic acid
• CAS NO: 203792-23-8
• Molecular Weight: 480.602
• Mol File: 203792-23-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-[2-(tert-butoxycarbonyl-tert-butoxycarbonylmethyl-amino)-3-cyclohexyl-propionyl]-2,5-dihydro-1H-pyrrole-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-(tert-butoxycarbonyl-tert-butoxycarbonylmethyl-amino)-3-cyclohexyl-propionyl]-2,5-dihydro-1H-pyrrole-2-carboxylic acid(203792-23-8)
• EPA Substance Registry System: 1-[2-(tert-butoxycarbonyl-tert-butoxycarbonylmethyl-amino)-3-cyclohexyl-propionyl]-2,5-dihydro-1H-pyrrole-2-carboxylic acid(203792-23-8)

Safety Data

• Hazardous Substances Data: 203792-23-8(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 151899-07-9 D-cyclohexylalanine hydrochloride 
• 144644-00-8 methyl (R)-2-amino-3-cyclohexylpropanoate hydrochloride 
• 190904-17-7 N-(tert-butyloxycarbonylmethyl)-D-Cha-OMe 
• 190904-21-3 (2R)-2-[(tert-butoxycarbonyl)(2-tert-butoxy-2-oxoethyl)amino]-3-cyclohexylpropanoic acid 
• 190904-19-9 N-(tert-butyloxycarbonylmethyl)-N-Boc-D-Cha-OMe 
• 203792-22-7 C₂₆H₄₂N₂O₇ 

Downstream Products

• 203792-69-2 C₃₃H₅₀N₄O₇S 
• 203793-01-5 C₂₉H₄₂N₆O₇ 
• 203792-55-6 C₃₁H₄₄N₄O₆S 
• 182291-43-6 tert-butyl {(tert-butoxycarbonyl)[(1R)-2-[(2S)-2-({[(6-cyano-3-pyridinyl)methyl]amino}carbonyl)-2,5-dihydro-1H-pyrrol-1-yl]-1-(cyclohexylmethyl)-2-oxoethyl]amino}acetate 
• 203792-91-0 [tert-butoxycarbonyl-(2-{2-[(5-carbamimidoyl-1-methyl-1H-pyrrol-2-ylmethyl)-carbamoyl]-2,5-dihydro-pyrrol-1-yl}-1-cyclohexylmethyl-2-oxo-ethyl)-amino]-acetic acid tert-butyl ester 

Relevant articles and documents

Orally active thrombin inhibitors. Part 1: Optimization of the P1-moiety

The synthesis and SAR of novel nanomolar thrombin inhibitors with the common backbone HOOC-CH2-d-cyclohexylalanyl-3,4-dehydroprolyl-NH-CH 2-aryl-C(double bond, long NH)NH2 are described together with their ecarin clotting