203864-63-5

Upstream product

• 50908-41-3 2,5-anhydro-3-deoxy-4,6-di-O-toluoyl-D-ribohexononitrile 
• 3601-89-6 Hoffer's chlorosugar 
• 452-51-7 D-2-deoxyribose 
• 4330-21-6 2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride 
• 51255-17-5 1-O-methyl-2-deoxy-D-ribofuranoside 
• 4330-34-1 methyl 3,5-di-O-toluoyl-2-deoxy-D-ribofuranose 

Downstream Products

• 203864-64-6 C₃₈H₃₁NO₆ 
• 605674-30-4 C₂₈H₂₈N₂O₆ 
• 605674-29-1 C₂₈H₂₇N₃O₈ 
• 184296-62-6 (2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-carboxylic acid methyl ester 
• 835639-57-1 (2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-carboxylic acid isobutyl-amide 
• 835639-59-3 (2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-carboxylic acid [2-(3H-imidazol-4-yl)-ethyl]-amide 
• 605674-33-7 C₂₈H₂₆N₂O₅ 
• 605674-34-8 C₂₇H₂₅N₃O₅ 
• 605674-32-6 C₂₈H₂₅N₃O₇ 
• 605674-39-3 C₂₈H₂₅N₃O₇ 
• 605674-41-7 C₃₀H₂₈N₂O₆ 
• 634178-95-3 C₃₃H₃₁N₃O₇S 
• 203864-66-8 Diisopropyl-phosphoramidous acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(pyren-1-ylcarbamoyl)-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester 
• 866757-12-2 N₂-benzoyl-4-[5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-β-D-erythro-pentofuranosyl]quinazoline 

Relevant academic research and scientific papers

Design of novel RNA ligands that bind stem-bulge HIV-1 TAR RNA

We report here the rational design and the synthesis of a new series of RNA ligands. These molecules are constituted of various binding motifs that interact cooperatively with HIV-1 TAR RNA, used as a model.

Synthesis of C-nucleosides designed to participate in triplex formation with native DNA: Specific recognition of an A:T base pair in DNA

We have previously described a system of 2-aminoquinoline- and 2-aminoquinazoline-based C-deoxynucleosides (TRIPsides) that are designed to be incorporated into oligomers that can specifically bind in the major groove via Hoogsteen base pairing to any seq

Introduction of peptide functions into DNA by nucleic acid peptides, NAPs

Nucleic acid peptides (NAPs) with a mimetic amino acid side residue at the base position of the nucleotide via an amide bond were synthesized from 3-deoxy-6-O-(4,4′-dimethoxytrityl)allonic acid methyl ester as the common precursor. Furthermore, an NAP with an octapeptide at the C1′ position was synthesized. The peptide-linked NAP exhibits both functions of the oligopeptide part and of the oligonucleotide part. Copyright

A short and efficient synthesis of 2′-deoxybenzo- and pyridoimidazole C-nucleosides

A short route to a series of 2′-deoxy-C-nucleosides featuring substituted nucleobases has been developed. The key step is the formation of the cyclized products following Mukaiyama's type amide coupling and a simple dehydration, starting from readily accessible synthons. The epimerization of the C1′-stereogenic center was avoided under mild and controlled conditions.

Synthesis of a novel pyrene-containing nucleoside and its incorporation into oligonucleotides

The synthesis of the aryl nucleoside analogue β-2'-deoxy-D-ribofuranosyl-1'-N-pyrenyl-carboxamide is described. This compound can be converted into a phosphoramidite reagent and used in solid phase oligonucleotide synthesis.