203866-60-8

Basic information

• Product Name: 4-tert-Butyl-N-{9-[(2R,3R,3aR,9aR)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yloxy)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl]-9H-purin-6-yl}-benzamide
• CAS NO: 203866-60-8
• Molecular Weight: 815.086
• Mol File: 203866-60-8.mol

Chemical Properties

• CAS DataBase Reference: 4-tert-Butyl-N-{9-[(2R,3R,3aR,9aR)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yloxy)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl]-9H-purin-6-yl}-benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-tert-Butyl-N-{9-[(2R,3R,3aR,9aR)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yloxy)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl]-9H-purin-6-yl}-benzamide(203866-60-8)
• EPA Substance Registry System: 4-tert-Butyl-N-{9-[(2R,3R,3aR,9aR)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yloxy)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl]-9H-purin-6-yl}-benzamide(203866-60-8)

Safety Data

• Hazardous Substances Data: 203866-60-8(Hazardous Substances Data)

Upstream product

• 1710-98-1 p-tert-butyl benzoyl chloride 
• 203866-59-5 2-[(2R,3R,3aR,9aR)-2-(6-Amino-purin-9-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yloxy]-isoindole-1,3-dione 
• 524-38-9 N-hydroxyphthalimide 
• 88121-25-9 9-[3′,5′-O-(1,1,3,3-tetraisopropyldisiloxyl)-2′-O-trifluormethylsulfonyl-β-D-arabinofuranosyl]adenine 
• 87792-02-7 9-[3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-1-β-D-arabinofuranosyl]adenine 
• 13154-24-0 triisopropylsilyl chloride 

Downstream Products

• 203866-65-3 4-tert-Butyl-N-{9-[(2R,3R,4R,5R)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yloxy)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl]-9H-purin-6-yl}-benzamide 
• 203866-66-4 N-{9-[(2R,3R,4R,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yloxy)-4-hydroxy-tetrahydro-furan-2-yl]-9H-purin-6-yl}-4-tert-butyl-benzamide 

Relevant articles and documents

Highly efficient synthesis of 2'-O-amino nucleosides and their incorporation in hammerhead ribozymes

2'-O-Amino nucleosides were prepared from arabino nucleosides by triflate displacement with N-hydroxy phthalimide. The corresponding phosphoramidites suitable for automated oligonucleotide synthesis, were also prepared. Incorporation of 2'-O-amino uridine into position U7 of 2'-O-amino adenosine into position A9 of a hammerhead ribozyme resulted in a slight improvement of catalytic rates.