203915-49-5Relevant articles and documents
Preparation method of 2, 4-dichloro-3, 5-dinitrobenzotrifluoride
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Paragraph 0023-0024; 0027-0028, (2020/08/25)
The invention discloses a preparation method of 2, 4-dichloro-3, 5-dinitrobenzotrifluoride, and the method comprises the following steps: carrying out first-step nitration reaction by using 2, 4-dichlorobenzotrifluoride as a raw material, and carrying out phase separation to obtain waste acid and a nitration intermediate after the reaction; mixing fuming nitric acid and fuming sulfuric acid to form mixed acid, carrying out a second-step nitration reaction on the mixed acid and the nitration intermediate, and carrying out phase separation after the reaction to obtain semi-waste acid and the target compound 2, 4-dichloro-3, 5-dinitrobenzotrifluoride, wherein the semi-waste acid separated from the nitration reaction in the second step can be directly recycled in the nitration reaction in thefirst step, and is mixed with the 2, 4-dichlorobenzotrifluoride to perform a new round of nitration reaction. According to the preparation method of the 2, 4-dichloro-3, 5-dinitrobenzotrifluoride, disclosed by the invention, two-step reaction is carried out under normal pressure, the operation is simple, and the purity of the finished product is high; the semi-waste acid generated in the second step of nitrification can be directly used in the first step of nitrification reaction, so that the circular economy is realized, and the waste acid discharge is reduced.