6656-72-0

Basic information

• Product Name: Benzenamine, 2,6-dichloro-3-(trifluoromethyl)-
• Synonyms: 2,6-Dichloro-3-(trifluoromethyl)aniline; 2,6-Dichloro-3-(trifluoromethyl)benzenamine; 2,6-Dichloro-α,α,α-trifluoro-m-toluidine; 6656-72-0; Benzenamine, 2,6-dichloro-3-(trifluoromethyl)-; ZR BG FG CXFFF
• CAS NO: 6656-72-0
• Molecular Formula: C₇H₄Cl₂F₃N
• Molecular Weight: 230.0146
• Mol File: 6656-72-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 235°C at 760 mmHg
• Flash Point: 95.9°C
• Appearance: /
• Density: 1.542g/cm³
• Vapor Pressure: 0.0512mmHg at 25°C
• Refractive Index: 1.518
• PKA: -0.51±0.10(Predicted)
• CAS DataBase Reference: Benzenamine, 2,6-dichloro-3-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 2,6-dichloro-3-(trifluoromethyl)-(6656-72-0)
• EPA Substance Registry System: Benzenamine, 2,6-dichloro-3-(trifluoromethyl)-(6656-72-0)

Safety Data

• HazardClass: 6.1
• Hazardous Substances Data: 6656-72-0(Hazardous Substances Data)

Usage

General Description

Benzenamine, 2,6-dichloro-3-(trifluoromethyl)- is a chemical compound that is used in the production of various pharmaceuticals, agrochemicals, and dyes. It is a derivative of aniline, with two chlorine atoms and a trifluoromethyl group attached to the benzene ring. Benzenamine, 2,6-dichloro-3-(trifluoromethyl)- is often used as an intermediate in the synthesis of other chemicals and is known for its strong nucleophilic and electrophilic properties. It is important to handle this chemical with care, as it can be hazardous to human health and the environment if not properly managed.

InChI:InChI=1/C7H4Cl2F3N/c8-4-2-1-3(7(10,11)12)5(9)6(4)13/h1-2H,13H2

Upstream product

• 121-50-6 3-amino-4-chlorobenzotrifluoride 
• 203915-49-5 1,3-dichloro-2-nitro-4-(trifluoromethyl)benzene 
• 2926-29-6 Langlois reagent 
• 608-31-1 2,6-Dichloroaniline 

Downstream Products

• 6690-41-1 2-(2,6-Dichloro-3-trifluoromethyl-phenylamino)-benzoic acid 

Relevant articles and documents

PYRIMIDINE UREA DERIVATIVES AS KINASE INHIBITORS

The invention relates to compounds of formula (I) wherein the substituents X1, R1, R2, R3 and R4 have the meaning as set forth and explained in the description of the invention, to processes for the preparation of these compounds, pharmaceutical compositions containing same, the use thereof optionally in combination with one or more other pharmaceutically active compounds for the therapy of a disease which responds to an inhibition of protein kinase activity, and a method for the treatment of such a disease.

Trifluoromethylation of aromatic compounds with sodium trifluoromethanesulfinate under oxidative conditions

Radical trifluoromethylation occurs without Cu(II) but cations are involved with Cu(II). Electron-rich aromatic compounds are triluforomethylated with sodium trifluoromethanesulfinate and t-butyl hydroperoxide. Monotrifluoromethylation predominates in the presence of catalytic amounts of Cu(II) triflate whereas mono- and bis-trifluoromethylated aromatics are obtained in almost equal quantities in the absence of Cu(II).

Novel substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides and compositions and method for inhibiting pollen formation in corn

Novel compounds, e.g., 5,7-dimethyl-N-(2,6-dichlorolphenyl)-1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamide and their compositions and use in the control of weeds and in the suppression of nitrification of ammonium nitrogen in soil. Other novel compounds and their compositions and use in the inhibition of bolting in sugar beets. Other novel compounds and their compositions and use as plant gametocides.