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2,8-Diaza-spiro[4.5]decane-3,8-dicarboxylic acid 8-tert-butyl ester 3-ethyl ester is a complex organic chemical compound featuring a spirocyclic ring system with carboxylic acid and ester groups. 2,8-Diaza-spiro[4.5]decane-3,8-dicarboxylic acid 8-tert-butyl ester 3-ethyl ester is distinguished by its diaza-spirodecane ring and the presence of both a tert-butyl and an ethyl ester group, which contribute to its unique molecular structure and potential applications in various fields.

203934-60-5

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203934-60-5 Usage

Uses

Used in Organic Synthesis:
2,8-Diaza-spiro[4.5]decane-3,8-dicarboxylic acid 8-tert-butyl ester 3-ethyl ester is used as a building block in organic synthesis for the creation of new compounds. Its unique structure allows for versatile chemical reactions, making it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2,8-Diaza-spiro[4.5]decane-3,8-dicarboxylic acid 8-tert-butyl ester 3-ethyl ester is used as a precursor in drug development. Its distinctive molecular framework can be utilized to design and synthesize novel pharmaceuticals with potential therapeutic applications.
Used in Materials Science:
2,8-Diaza-spiro[4.5]decane-3,8-dicarboxylic acid 8-tert-butyl ester 3-ethyl ester is also used in materials science for the development of new materials. Its structural properties may contribute to the creation of innovative materials with unique properties, such as improved stability or specific interactions with other molecules.
Further research on the properties and potential applications of 2,8-Diaza-spiro[4.5]decane-3,8-dicarboxylic acid 8-tert-butyl ester 3-ethyl ester could lead to significant advancements in various scientific and industrial fields, including drug development and materials science.

Check Digit Verification of cas no

The CAS Registry Mumber 203934-60-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,3,9,3 and 4 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 203934-60:
(8*2)+(7*0)+(6*3)+(5*9)+(4*3)+(3*4)+(2*6)+(1*0)=115
115 % 10 = 5
So 203934-60-5 is a valid CAS Registry Number.

203934-60-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,8-Diazaspiro[4.5]decane-3,8-dicarboxylic acid 8-tert-butyl ester 3-ethyl ester

1.2 Other means of identification

Product number -
Other names 8-O-tert-butyl 3-O-ethyl 2,8-diazaspiro[4.5]decane-3,8-dicarboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:203934-60-5 SDS

203934-60-5Relevant articles and documents

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Novel spiroketal pyrrolidine GSK2336805 potently inhibits key hepatitis C virus genotype 1b mutants: From lead to clinical compound

Kazmierski, Wieslaw M.,Maynard, Andrew,Duan, Maosheng,Baskaran, Sam,Botyanszki, Janos,Crosby, Renae,Dickerson, Scott,Tallant, Matthew,Grimes, Rick,Hamatake, Robert,Leivers, Martin,Roberts, Christopher D.,Walker, Jill

, p. 2058 - 2073 (2014/04/03)

Rapid clinical progress of hepatitis C virus (HCV) replication inhibitors, including these selecting for resistance in the NS5A region (NS5A inhibitors), promises to revolutionize HCV treatment. Herein, we describe our explorations of diverse spiropyrrolidine motifs in novel NS5A inhibitors and a proposed interaction model. We discovered that the 1,4-dioxa-7-azaspiro[4.4]nonane motif in inhibitor 41H (GSK2236805) supported high potency against genotypes 1a and 1b as well as in genotype 1b L31V and Y93H mutants. Consistent with this, 41H potently suppressed HCV RNA in the 20-day RNA reduction assay. Pharmacokinetic and safety data supported further progression of 41H to the clinic.

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