203934-93-4

Basic information

• Product Name: (R)-2-{(S)-[(4S,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidin-4-yl]-hydroxy-methyl}-3-methyl-butyric acid methyl ester
• Synonyms: (R)-2-{(S)-[(4S,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidin-4-yl]-hydroxy-methyl}-3-methyl-butyric acid methyl ester
• CAS NO: 203934-93-4
• Molecular Weight: 493.759
• Mol File: 203934-93-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-2-{(S)-[(4S,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidin-4-yl]-hydroxy-methyl}-3-methyl-butyric acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-{(S)-[(4S,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidin-4-yl]-hydroxy-methyl}-3-methyl-butyric acid methyl ester(203934-93-4)
• EPA Substance Registry System: (R)-2-{(S)-[(4S,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidin-4-yl]-hydroxy-methyl}-3-methyl-butyric acid methyl ester(203934-93-4)

Safety Data

• Hazardous Substances Data: 203934-93-4(Hazardous Substances Data)

Upstream product

• 120420-10-2 (E)-((1-methoxy-3-methylbut-1-en-1-yl)oxy)trimethylsilane 
• 145451-93-0 (4R,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidine-4-carboxylic acid methyl ester 
• 145452-01-3 [(4R,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidin-4-yl]-methanol 
• 145451-90-7 (2R,4R)-3-Benzyl-2-tert-butyl-4-((S)-1-hydroxy-2-methyl-propyl)-oxazolidine-4-carboxylic acid methyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 31469-15-5 1-methoxy-2-methyl-1-trimethylsiloxy-1-propene 
• 145484-22-6 (4R,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidine-4-carbaldehyde 

Relevant articles and documents

The structural requirements for inhibition of proteasome function by the lactacystin-derived β-lactone and synthetic analogs

The synthesis of analogs of the lactacystin-derived β-lactone (2) in which the substituents at C(5), C(7) and C(9) were systematically varied has led to a well defined structure-activity correlation for the highly selective inhibition of the mammalian 20 S proteasome.