145484-22-6

Basic information

• Product Name: (4R,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidine-4-carbaldehyde
• Synonyms: (4R,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidine-4-carbaldehyde
• CAS NO: 145484-22-6
• Molecular Weight: 377.599
• Mol File: 145484-22-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4R,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidine-4-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidine-4-carbaldehyde(145484-22-6)
• EPA Substance Registry System: (4R,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidine-4-carbaldehyde(145484-22-6)

Safety Data

• Hazardous Substances Data: 145484-22-6(Hazardous Substances Data)

Upstream product

• 145452-01-3 [(4R,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidin-4-yl]-methanol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 145451-90-7 (2R,4R)-3-Benzyl-2-tert-butyl-4-((S)-1-hydroxy-2-methyl-propyl)-oxazolidine-4-carboxylic acid methyl ester 
• 145451-93-0 (4R,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidine-4-carboxylic acid methyl ester 
• 145451-91-8 (2R,3S)-2-Benzylamino-3-hydroxy-2-hydroxymethyl-4-methyl-pentanoic acid methyl ester 

Downstream Products

• 145552-70-1 (2S,3R)-3-[(4S,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidin-4-yl]-3-hydroxy-2-methyl-propionic acid 2,6-dimethyl-phenyl ester 
• 203934-93-4 (R)-2-{(S)-[(4S,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidin-4-yl]-hydroxy-methyl}-3-methyl-butyric acid methyl ester 
• 203934-94-5 (2R,3S)-2-Benzyl-3-[(4S,5S)-3-benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidin-4-yl]-3-hydroxy-propionic acid methyl ester 
• 203934-91-2 (R)-2-{(S)-[(4S,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidin-4-yl]-hydroxy-methyl}-butyric acid methyl ester 
• 203934-92-3 (R)-2-{(S)-[(4S,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidin-4-yl]-hydroxy-methyl}-hexanoic acid methyl ester 
• 203935-00-6 (1S,6R,7S,7aS)-6-Benzyl-7-hydroxy-7a-hydroxymethyl-1-isopropyl-tetrahydro-pyrrolo[1,2-c]oxazol-5-one 
• 145452-03-5 (1S,6R,7S,7aS)-7-Hydroxy-1-isopropyl-6-methyl-5-oxo-dihydro-pyrrolo[1,2-c]oxazole-7a-carbaldehyde 
• 145452-02-4 (1S,6R,7S,7aS)-7-Hydroxy-7a-hydroxymethyl-1-isopropyl-6-methyl-tetrahydro-pyrrolo[1,2-c]oxazol-5-one 
• 145451-96-3 (1S,6R,7S,7aS)-7-Hydroxy-1-isopropyl-6-methyl-5-oxo-dihydro-pyrrolo[1,2-c]oxazole-7a-carboxylic acid 
• 133343-34-7 Lactacystin 
• 154226-60-5 omuralide 
• 145451-95-2 (1S,6R,7S,7aS)-7a-(tert-Butyl-dimethyl-silanyloxymethyl)-7-hydroxy-1-isopropyl-6-methyl-tetrahydro-pyrrolo[1,2-c]oxazol-5-one 
• 145451-97-4 (3R,4S,5R,1'S)-4-hydroxy-5-(1'-hydroxy-2'-methylpropyl)-3-methylpyrrolidin-2-one-5-carboxylic acid 
• 203934-88-7 (2R,3S)-3-[(4S,5S)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-isopropyl-oxazolidin-4-yl]-3-hydroxy-2-methyl-propionic acid methyl ester 

Relevant articles and documents

A new magnesium-catalyzed doubly diastereoselective anti-aldol reaction leads to a highly efficient process for the total synthesis of lactacystin in quantity

A new process is described for metal-catalyzed doubly diastereoselective Mukaiyama aldol coupling of a chiral tertiary α-amino aldehyde and an achiral silyl enol ether to form selectively an anti-aldol product. The metal requirement is strict, since of se