20406-82-0 Usage
General Description
2',3'-O-Isopropylidene 5-hydroxyuridine is a chemical compound that is commonly used in the synthesis of nucleoside analogues. It is a modified form of the nucleoside uridine, with an isopropylidene group attached to the 2' and 3' hydroxyl groups, and a hydroxy group attached to the 5' carbon. This modification serves to protect the hydroxyl group and prevent unwanted reactions during chemical synthesis. The compound has potential applications in antiviral and anticancer drug development, as well as in the study of nucleic acid structure and function. Its unique structure and functional properties make it a versatile building block for the synthesis of nucleoside analogues with various biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 20406-82-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,4,0 and 6 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 20406-82:
(7*2)+(6*0)+(5*4)+(4*0)+(3*6)+(2*8)+(1*2)=70
70 % 10 = 0
So 20406-82-0 is a valid CAS Registry Number.
20406-82-0Relevant articles and documents
Synthesis of some hydroxamic acids related to uridine: Potential inhibitors of ribonucleoside diphosphate reductase
Currid, Peter,Wightman, Richard H.
, p. 115 - 128 (2007/10/03)
5-(N-Hydroxy)carboxamidouridine (5) and 5-(N-hydroxy)carboxamido- methyluridine (6) have been synthesized; these hydroxamic acids incorporate a radical trap into a nucleoside structure, and are designed as potential inhibitors of ribonucleotide diphosphat
Reactions of 5-bromo substituted pyrimidine nucleosides with aqueous alkalies: kinetics and mechanisms.
K?ppi,L?nnberg
, p. 768 - 775 (2007/10/02)
Kinetics for the parallel and consecutive steps of the reactions of 5-bromocytidine, 5-bromouridine and its 5'-O-methyl and 2',3'-O-isopropylidene derivatives with aqueous alkalies were studied by LC. The mechanisms of the partial reactions involved are discussed.