204073-95-0Relevant academic research and scientific papers
Highly diastereoselective Diels-Alder reactions with enantiopure sulfinyl-substituted 1-hydroxymethyldienes
De La Pradilla, Roberta Fernandez,Montero, Carlos,Tortosa, Mariola,Viso, Aima
, p. 5136 - 5145 (2007/10/03)
Enantiopure hydroxy-2- and -3-sulfinyldienes undergo highly selective Diels-Alder cycloadditions with various dienophiles controlled by the chiral sulfur atom. The related hydroxy-2-sulfonyldienes display complementary π-facial selectivity.
Sulfur-Directed Synthesis of Enantiopure Hydroxy 2-Sulfinyl Butadienes
Fernandez De La Pradilla, Roberto,Buergo, Maria Victoria,Martinez, Maria Victoria,Montero, Carlos,Tortosa, Mariola,Viso, Alma
, p. 1978 - 1986 (2007/10/03)
The treatment of sulfinyl chlorohydrins with KO-t-Bu in THF generates epoxy vinyl sulfoxides that undergo an efficient base-induced rearrangement to generate enantiopure hydroxy 2-sulfinyl dienes. This novel process takes place with high chemo- and stereo
