198987-18-7

Upstream product

• 19261-37-1 2-chloro-3-phenyl-propionaldehyde 
• 61187-72-2 (R)-(1-Butenyl)-p-tolyl-sulfoxid 
• 198987-11-0 (+)-(2R,3S,S_S)-(4E)-2-chloro-1-phenyl-4-(p-tolylsulfinyl)hept-4-en-3-ol 

Downstream Products

• 204073-95-0 (+)-(2S)-(3Z,5E)-1-phenyl-7-(p-tolylsulfonyl)hepta-3,5-dien-2-ol 
• 204073-90-5 (-)-(3aR,4S,7S,7aR,S_S)-4-[(1S)-hydroxy-2-phenylethyl]-7-methyl-2-phenyl-5-(p-tolylsulfinyl)-1,3,3a,4,7,7a-tetrahydro-2H-isoindole-1,3-dione 

Relevant academic research and scientific papers

Sulfur-directed synthesis of enantiopure hydroxy 2-sulfinyl butadienes

Epoxy vinyl sulfoxides, generated in situ from sulfinyl chlorohydrins, undergo an efficient base-induced rearrangement to generate enantiopure hydroxy 2-sulfinyl dienes. The chiral sulfur auxillary controls the E-Z stereoselectivity of the trisubstituted

Sulfur-Directed Synthesis of Enantiopure Hydroxy 2-Sulfinyl Butadienes

The treatment of sulfinyl chlorohydrins with KO-t-Bu in THF generates epoxy vinyl sulfoxides that undergo an efficient base-induced rearrangement to generate enantiopure hydroxy 2-sulfinyl dienes. This novel process takes place with high chemo- and stereo